INTRODUCTION Biomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting. CASE PRESENTATION A 33-year-old Asian female who underwent penetrating keratoplasty in both eyes developed corneal melting in the right eye and marginal keratitis in the left eye in her fifth month of pregnancy. Marginal keratitis in the left eye imme...

A total of 2,905 children between 6 and 71 months of age were selected using a 2 stage stratified sampling method and screened for xerophthalmia using World Health Organisation (WHO) criteria and vitamin a deficiency (VAD) using serum retinol < 20 μg/dl (low/marginal). Only 33 cases of xerophthalmia were seen representing a national prevalence of 1.1%. Only 8 children presented with Bitot’s spo...

The onset of bilateral necrotising scleritis and marginal corneal ulceration after cataract surgery are described in a patient with diffuse vasculitis syndrome. The finding of immune complexes in this patient's tissue biopsy suggests that they are the cause of a localised primary vasculitis triggered by surgical inflammation. Clinically, this patient's marginal corneal ulceration preceded the s...

Koby in 1927 described a progressive, superficial corneal degeneration in a middle-aged woman that led to a painless loss of vision. This condition was characterized by the appearance of a central, fine, white reticulum at the level of Bowman's layer. The epithelium was thickened and bedewed, giving a faint brownish opalescence and providing a striking contrast to the white reticulum. We evalua...

Salzmann’s corneal nodular degeneration has been defined as a degenerative process that follows episodes of keratitis. The diagnosis is based on the presence of elevated nodules above the surface of the cornea, usually at the periphery. The condition appears commonly associated with a history of scarlet fever, measles, trachoma, vernal keratoconjunctivitis, or phlyctenular keratoconjunctivitis ...

PURPOSE To report the clinicopathological findings of a Chinese patient with an unusual phenotype of gelatinous drop-like corneal dystrophy (GDLD) combined with spheroidal degeneration and to detect molecular defect in the tumor-associated calcium signal transducer 2 (TACSTD2) gene. METHODS Extensive physical and ophthalmologic examination of the patient was performed. Initially superficial k...