Shear thickening fluids (STFs) have been shown to improve the effectiveness of fabrics used in soft body armor applications. They are increase puncture and ballistic impact resistance Kevlar® fabrics. However, effect using STFs with natural such as flax appears never studied. Similarly, hybridization different fabric types impregnated STF has also only undergone limited study. The rheology at v...

in this study a 3-factor, 3-level box-behnken design was used to prepare optimized docetaxel (dtx) loaded pegylated poly lactide-co-glycolide (peg-plga) nps with polymer concentration (x1), drug concentration (x2) and ratio of the organic to aqueous solvent (x3) as the independent variables and particle size (y1), poly dispersity index (pdi) (y2) and drug loading (y3) as the responses. the cyto...

Human interferon (IFN) β has well established beneficial effects in treating relapsing forms of multiple sclerosis, but current first-line treatment requires frequent (from daily to weekly) parenteral administration. A 20-kDa polyethylene glycol (PEG)-conjugated IFN β-1a (PEG-IFN β-1a) is being developed to decrease the frequency of administration and improve patient convenience and compliance....

In experiments on digestive function in ruminants, markers can be used to estimate the rate of movement of digesta, the volume of a viscus and the rates of absorption of solutes from the gut. The most widely used water-soluble marker is polyethylene glycol (PEG), which was introduced by Sperber, HydCn & Ekman (1953). They found that the polymer with mean molecular weight 4000 was not degraded i...

Three new amphiphilic molecules were synthetized on a basis of common monomer, octadecyl succinic anhydride (OSA), which grafted different PEGylated hydrophilic polar head. The objective this study is to investigate potential relationship between the chemical structure surfactant, and efficiency generate nano-emulsions through spontaneous nano-emulsification method. Beyond innovative synthesis ...

The distribution of intramembrane particles (IMP) as revealed by freeze-fracture electron microscopy has been analyzed following treatment of mouse L cells and fusion-deficient L cell derivatives with several concentrations of polyethylene glycol (PEG). In cell cultures treated with concentrations of PEG below the critical level for fusion, no aggregation of IMP was observed. When confluent cul...

Wheat is an important cereal crop worldwide that often suffers from moisture deficits at the reproductive stage. Polyethylene glycol (PEG)-treated hydroponic conditions create negative osmotic potential which is compared with moisture deficit stress. An experiment was conducted in a growth chamber to study the effects of PEG on root hair morphology and associated traits of wheat varieties. Plan...

Two poly(ethylene glycol) (PEG)-peptides were synthesized and tested for their ability to bind to plasmid DNA and form soluble DNA condensates with reduced spontaneous gene expression. PEG-vinyl sulfone or PEG-orthopyridyl disulfide were reacted with the sulfhydryl of Cys-Trp-Lys(18) (CWK(18)) resulting in the formation of nonreducible (PEG-VS-CWK(18)) and reducible (PEG-SS-CWK(18)) PEG-peptide...

In this work, racemic hybrid polypeptides poly(ethylene glycol) (PEG)-b-poly(racemic-leucine) (PRL) copolymers with different leucine residues have been synthesized and characterized. Using docetaxel as a model molecule, the high drug-loaded spherical micelles based on PEG-PRL were prepared successfully using dialysis, with a tunable particle size from 170 nm to 250 nm obtained by changing the ...

The aim of the study was to evaluate a hot-melt technique for preparation of immediate release spherical microparticles containing clarithromycin with acceptable characteristics and process yield. A modified fluid bed apparatus with rotor insert was used to prepare spherical microparticles in the size range of 125-355 µm. Poloxamer 188, PEG-32 glyceryl laurate (Gelucire 44/14) and a mixture of ...