The bone morphogenetic protein (BMP) pathway is known to be involved in limb myogenesis during development, but whether it is involved in postnatal muscle regeneration is unclear. We have found that adult inhibitor of differentiation (Id)-mutant (Id1(+/-)Id3(-/-)) mice display delayed and reduced skeletal muscle regeneration after injury compared with either wild-type littermates or Id3-null mi...

To determine whether muscle satellite cells and utrophin are correlated with the degree of damage in mdx skeletal muscles, we measured the area of the degenerative region as an indicator of myofiber degeneration in the masseter, gastrocnemius, soleus, and diaphragm muscles of mdx mice. Furthermore, we analyzed the expression levels of the paired box homeotic gene 7 (pax7), m-cadherin (the maker...

Approximately 90% of beef cattle on feed in the United States receive at least one anabolic implant, which results increased growth, efficiency, and economic return to producers. However, complete molecular mechanism through implants function improve skeletal muscle growth remains unknown. This study had 2 objectives: (1) determine effect polyamines their precursors proliferation rate bovine sa...

[Purpose] This study investigated the effect of aging on muscle regeneration in rats. [Participants and Methods] Male Wistar rats were divided into 3 groups 10-week-old, 24-week-old, 95-week-old animals. We administered a cardiotoxin to soleus create skeletal injury model, physiological analysis histological was performed at 1, 2, 4, 7, 14, 28 days after administration. [Results] The cross-sect...