Gestational trophoblastic disease corresponds to cystic degeneration of the trophoblast villi with excessive secretion choriogonatrophinic hormone (HCG), groups together lesions : · Benign known as hydatidiform moles (partial or complete) Malignant gestational tumors (GTT), comprising o Choriocarcinomas Invasive Trophoblastic implantation site (TTSI) Diagnosis is based on questioning and clinic...

Gestational trophoblastic disease (MTG) groups together conditions that are very variable from a clinical, biological and metastatic potential point of view.We report case ruptured molar pregnancy, diagnosed by picture hemorrhagic shock, confirmed histological examination the surgical specimen. Monitoring was assaying plasma BhCG levels.

OBJECTIVE The aim of this study was to determine the oxidative status and antioxidative status of plasma of patients with complete hydatidiform mole (CHM) and to compare these values with normal pregnancy. METHOD Thirty-eight patients with CHM and 31 healthy pregnant women were enrolled in the study. To determine the antioxidative status of plasma, total antioxidant potential (TAOP) was calcu...

Leptin and insulin are secreted into the maternal and to a lesser extent into the fetal bloodstream where they act as placental signals and nourish the fetus, making them possible candidates for the endocrine control of the placenta. We investigated differences in leptin (LR) and insulin receptors (IR) expression in normal and disturbed first trimester human pregnancy at protein level by immuno...

Among 2,968 women and girls exposed to crocidolite (blue asbestos) at Wittenoom, three cases of choriocarcinoma and three cases of hydatidiform mole have been identified (crude incidence rate of 9.9 per 1000 women and 1.7 per 1000 deliveries for choriocarcinoma and hydatidiform mole, respectively). The women with choriocarcinoma were resident at Wittenoom at the time of disease development, whe...

BACKGROUND Gestational choriocarcinoma is the most common gestational trophoblastic neoplasia; it is often secondary to hydatidiform mole, as well as to abortion, ectopic pregnancy, premature delivery, or term delivery. Approximately 60% of patients with choriocarcinoma develop pulmonary metastases, but for patients with a respiratory condition, choriocarcinoma with lung metastasis is a relativ...