Salivary gland cancers are uncommon malignancies of the head and neck region. Their site of origin can be major (parotid, submandibular and sublingual) or minor salivary gland (palate, nasal cavity, paranasal sinuses, trachea and lacrimal gland). Of all the salivary gland neoplasms, 85% are benign and 15% are malignant. Salivary gland malignancies comprise 3-6% of all head and neck cancers (Pin...

BACKGROUND There are still controversies about the therapeutic strategies and subsequent outcome in head and neck Merkel cell carcinoma. METHODS Clinicopathological data of 23 Merkel cell carcinomas, 93 cutaneous head and neck squamous cell carcinomas (HNSCCs), 126 malignant melanomas, and 91 primary parotid gland carcinomas were comprehensively analyzed. Merkel cell carcinomas were cytokerat...

OBJECTIVES The current study aimed to characterize comparatively the binding of imidafenacin to muscarinic receptors in the human bladder mucosa and detrusor muscle and parotid gland. METHODS The muscarinic receptor in homogenates of human tissues (bladder mucosa and detrusor muscle and parotid gland) was measured using a radioligand binding assay with [N-methyl-(3) H]scopolamine methyl chlor...

Parotid lymph node (LN) metastasis occurs most commonly from cutaneous squamous cell carcinoma (CSCC) of the head and neck, but rarely from oral squamous cell carcinoma (OSCC). Here, we present a rare case of metastasis to the parotid LN in a patient with tongue cancer. Although usual extent of modified radical neck dissection that includes resection of the tail of the parotid gland is below th...

Purpose To explore the distribution of node spread from lymphoepithelial-like carcinoma (LELC) of the parotid gland based on the 2013 updated guidelines for neck node levels. Results 42 (58.3%) cases had metastatic nodes, all were localized at the ipsilateral neck. The detailed distribution was: level Ia 0, level Ib 6(14.3%), level II 34 (80.1%), level III 16 (38.1%), level IV 9 (21.4%), leve...

The objective of this nationwide study was to assess the association between cellular phone use and development of parotid gland tumors (PGTs). The methods were based on the international INTERPHONE study that aimed to evaluate possible adverse effects of cellular phone use. The study included 402 benign and 58 malignant incident cases of PGTs diagnosed in Israel at age 18 years or more, in 200...

A patient presented 3 1/2 years after resection of a malignant parotid tumor with a new cerebellopontine angle mass. The presence of multiple punctate calcifications and loss of T2 signal were helpful in correctly identifying the lesion as mucinous adenocarcinoma.

OBJECTIVES This study evaluates the interobserver variation in parotid gland delineation and its impact on intensity-modulated radiotherapy (IMRT) solutions. METHODS The CT volumetric data sets of 10 patients with oropharyngeal squamous cell carcinoma who had been treated with parotid-sparing IMRT were used. Four radiation oncologists and three radiologists delineated the parotid gland that h...

Isoproterenol is a potent B-adrenergic agonist which its effect on rabbit salivary Glands has been studied in this research.two groups of male albino rabbits(five in each group with the mean weight of 1000+_300 gr) were injected with 20 mg/kg of  isoproterenol intrapritoneally each day for fifteen days and one similar group(n=5) was chosen as control group.in one of the test groups in addition ...

Benign lymphoepithelial cysts of the parotid are common in retropositive patients, but extremely rare in HIV-negative individuals. We present a 28-year-old man who presented with a painless, gradually increasing swelling in the left parotid region and was clinically diagnosed to have a pleomorphic adenoma of the left parotid gland. Preoperative blood investigations revealed that the patient was...