Abstract Malnutrition is observed in around one three hospital inpatients; this harmful ICD10-AM-coded disease a strong independent predictor of adverse older adult and healthcare outcomes, mortality, treatment costs globally, particularly multimorbid, adults. Despite recognition malnutrition as disease, nutrition support prescriptions are often not valued the medicine to treat it. This chapter...

OBJECTIVES The development of hyperglycemia and the use of early parenteral feeding are associated with poor outcomes in critically ill patients. We therefore examined the impact of exogenous glucose administration on the integrated metabolic function of endotoxemic mice using our recently developed frequently sampled intravenous glucose tolerance test (FSIVGTT). We next extended our findings u...

OBJECTIVE To study the effect of minimal enteral feeding (MEF) on intestinal permeability and feeding tolerance in preterm infants with intrauterine growth retardation (gestational age < 37 weeks, birth weight for gestational age p < 10). Furthermore, to determine whether fetal blood flow pulsatility or intestinal permeability predict feeding tolerance in these infants. DESIGN Randomised cont...

A 29 year old man with a history of childhood polymyositis developed insulin dependent diabetes and was found coincidentally to have chronic intestinal pseudo-obstruction due to visceral myopathy. Multiple full thickness biopsy specimens showed severe disease in the duodenum and the proximal jejunum only, with less involvement distally. Total parenteral nutrition has been avoided for more than ...

T he need to avoid prolonged starvation in patients is well recognized. More recently, it has been realized that without intraluminal fuels, intestinal integrity may deteriorate and allow translocation of gut bacteria. One means to combat nutrient deprivation and simultaneously to keep the local defense barrier of the intestine intact is tube feeding, i.e., enteral nutrition. This technique has...

Anorexia nervosa presenting as Wernicke-Korsakoff syndrome is rare. The causes of Wernicke-Korsakoff syndrome are multiple like alcohol abuse, thyrotoxicosis, haemodialysis, severe malnutrition because of gastric carcinoma and pyloric obstruction, hyperemesis gravidarum, and prolonged parenteral feeding. We report a case of anorexia nervosa, who presented with Wernicke's encephalopathy and prog...

Dietary and nutritional therapies encompass preventive and educational approaches to diet and lifestyle changes, in order to promote and optimise physical and mental health. They encompass personalised dietary therapy and nutraceutical prescription, and lifestyle advice within a functional medicine framework. This represents a nutritional paradigm different to that which underpins current diete...

A 29 year old man with a history of childhood polymyositis developed insulin dependent diabetes and was found coincidentally to have chronic intestinal pseudo-obstruction due to visceral myopathy. Multiple full thickness biopsy specimens showed severe disease in the duodenum and the proximal jejunum only, with less involvement distally. Total parenteral nutrition has been avoided for more than ...

[1] Page RD, Oo AY, Russell GN, Pennefather SH. Intravenous hydration versus naso-jejunal feeding after esophagectomy: a randomized study. Eur J Cardiothorac Surg 2002;22:666–72. [2] Gerndt SJ, Orringer MB. Tube jejunostomy as an adjunct to esophagectomy. Surgery 1994;115:164–9. [3] Baigrie RJ, Devitt PG, Watkin DS. Enteral versus parenteral nutrition after esophagogastric surgery: a prospectiv...

Seventeen infants with nodular purpura are reported. All these infants suffered from a coagulation abnormality due to vitamin K deficiency. Contributing factors were breast-feeding, the use of milk substitutes, diarrhoea and antimicrobial therapy. The patients responded rapidly and completely to parenteral vitamin K. In the management of infantile diarrhoea use of antibiotics should be restrict...