1162 ALTHOUGH CHANGES IN DREAMING DURING PREGNANCY ARE RELATIVELY WELL STUDIED,1-4 THOSE ASSOCIATED WITH THE POSTPARTUM STATE ARE NOT. We have observed informally that many new mothers describe acting out vivid disturbing nightmares about their new infants. A typical episode, which we dubbed the baby-in-bed (BIB) nightmare pattern, involves a dream that the infant has been lost in the mother’s ...

AIM Our aim was to review basic aspects of sleep disorders in children with Down syndrome in the light of present-day findings of such disorders in children in general, including other groups of children with developmental disabilities. METHODS A literature search of adverse developmental effects of sleep disturbance, types of sleep disturbance in children with Down syndrome, their aetiology,...

Sleep is known to be severely altered in temporal lobe epilepsy (TLE). Furthermore, sleep deprivation is one of the key factors contributing to cognitive deficits and drug resistance in TLE. In the past, "non-ictal" parasomnias, as well as parasomnia-like nocturnal episodes ultimately diagnosed as seizures, have been documented in epileptic patients. However, recurrence of possibly "ictal" para...

BACKGROUND Paroxysmal sleep disorders in children are important from both pathophysiological and clinical point of view. Correct diagnosis is crucial for further management. The aim of the present study was to identify peripheral markers of paroxysmal sleep disorders in children, which could improve diagnostics of these disorders. We compared serum levels of several putative biomarkers of neuro...

We read with great interest the paper by Lidia Sabater and colleagues, who describe a novel neuroimmuno logical disease that is a complex, severe sleep disorder associated with antibodies to IgLON5. We have noted a clinically similar disorder in a single patient who had serum and CSF antibodies to the metabotropic GABAB receptor. Similar to the patients in Sabater and colleagues’ report, our pa...

BACKGROUND/AIMS In a questionnaire survey, we identified 36 (9%) of 417 Parkinson's disease (PD) patients with sleepwalking (SW); 72% of them also had a history of REM sleep behaviour disorder (RBD). We aimed to assess the clinical and polysomnographic characteristics of SW in PD and to compare them to patients with PD with and without a history of RBD. METHODS We performed video-polysomnogra...

Four men, aged 67-72 years, had 4-month to 6-year histories of injuring themselves or their spouses with aggressive behaviors during sleep, often during attempted dream enactment. A 60-year-old woman had disruptive though nonviolent sleep and dream behaviors. Polysomnography did not detect seizures but did document REM sleep pathology with variable loss of chin atonia, extraordinarily increased...