نتایج جستجو برای: pandemic response

تعداد نتایج: 1076834  

Journal: :Vaccine 2011
Xin Zhou Janet E McElhaney

Age-dependent changes in the cellular immune response have been mainly described in CD8+ T cells, with relative sparing of CD4+ T cells. We show that in older compared to young adults, effector memory and effector CD8+ T-cell subsets responding to influenza A/H3N2 challenge have diminished cytolytic activity. In contrast, effector CD4+ T-cell subsets in older adults share similar phenotypic and...

2010
J. Jeremy Sueker David L. Blazes Matthew C. Johns Patrick J. Blair Paul A. Sjoberg Jeffrey A. Tjaden Joel M. Montgomery Julie A. Pavlin David C. Schnabel Angelia A. Eick Steven Tobias Miguel Quintana Kelly G. Vest Ronald L. Burke Luther E. Lindler Jay L. Mansfield Ralph Loren Erickson Kevin L. Russell Jose L. Sanchez

The US Department of Defense influenza surveillance system now spans nearly 500 sites in 75 countries, including active duty US military and dependent populations as well as host-country civilian and military personnel. This system represents a major part of the US Government's contributions to the World Health Organization's Global Influenza Surveillance Network and addresses Presidential Dire...

2013
John Iskander Raymond A. Strikas Kathleen F. Gensheimer Nancy J. Cox Stephen C. Redd

During the past century, 4 influenza pandemics occurred. After the emergence of a novel influenza virus of swine origin in 1976, national, state, and local US public health authorities began planning efforts to respond to future pandemics. Several events have since stimulated progress in public health emergency planning: the 1997 avian influenza A(H5N1) outbreak in Hong Kong, China; the 2001 an...

The COVID-19 pandemic has affected many people around the globe. Europe, as one of the most seriously affected continents, has been struggling with the novel coronavirus for several months. Obviously, outbreak response management plays a critical role in the impact of the disease. Therefore, in this paper, Malmquist Productivity Index is used to evaluate the performance of the most severely aff...

2017
Noreen Qualls Alexandra Levitt Neha Kanade Narue Wright-Jegede Stephanie Dopson Matthew Biggerstaff Carrie Reed Amra Uzicanin Alexandra Levitt Stephanie Dopson Mark Frank Rachel Holloway Lisa Koonin Sonja Rasmussen Stephen Redd Christopher de la Motte Hurst Neha Kanade Noreen Qualls Jeanette Rainey Amra Uzicanin Matthew Biggerstaff Daniel Jernigan Carrie Reed

When a novel influenza A virus with pandemic potential emerges, nonpharmaceutical interventions (NPIs) often are the most readily available interventions to help slow transmission of the virus in communities, which is especially important before a pandemic vaccine becomes widely available. NPIs, also known as community mitigation measures, are actions that persons and communities can take to he...

Introduction: Despite considerable efforts to control AIDS pandemic, it is still one of the significant infectious concerns worldwide. The advance in medical research has led to the development of highly active antiretroviral therapy with a considerable effect to suppress the disease. However, an effective vaccine capable of eradication the HIV pandemic is not available yet. Failure to develop ...

Differences in public health approaches to control the coronavirus disease 2019 (COVID-19) pandemic could largely explain substantial variations in epidemiological indicators (such as incidence and mortality) between the West and the East. COVID-19 revealed vulnerabilities of most western countries’ healthcare systems in their response to the ongoing public health crisi...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006
Jeffrey Levi Thomas Inglesby

Received 18 November 2005; accepted 18 November 2005; electronically published 29 November 2005 Trust for America’s Health (TFAH) is a nonprofit, nonpartisan organization dedicated to saving lives by protecting the health of every community and working to make disease prevention a national priority. Reprints or correspondence: Dr. Jeffrey Levi, Trust for America’s Health, 1707 H St. NW, Washing...

Introduction: Temporary medical centers can properly compensate for the shortage of hospitals during biological emergencies. They bolster the capacity of medical centers regarding patient admissions,  provide efficient care, and mitigate the progression of critical situations. This study aims to identify the advantages of setting up temporary medical centers in responding to the COVID-19 pandem...

2014
Shu Qiao Yang Jiu Xin Qu Chen Wang Xiao Min Yu Ying Mei Liu Bin Cao

INTRODUCTION Comparisons of the characteristics between the influenza A (H1N1) pdm09 and common seasonal influenza are important for both clinical management and epidemiological studies. However, the differences between pandemic and seasonal influenza during the post-pandemic period are poorly understood. OBJECTIVES The aim of our research was to investigate clinical and immune response diffe...

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