The majority of pancreatic cysts are detected incidentally when abdominal imaging is performed during unrelated procedures. The aim of the present study was to assess the diagnostic utility and clinical value of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9) and amylase analysis in pancreatic cyst fluid. The study included 52 patients with pancreatic cystic lesions, who und...

abstract distal pancreatectomy has been a standard technique for pancreatic body and tail lesions for years ago. recently, it is being performed laparoscopically in a perfect manner. there are two common methods for this procedure. one is distal pancreatectomy with splenectomy and the other is distal pancreatectomy with spleen preservation. in patients with splenic vessels involvement, it is no...

Background: Pancreatic tumor disease often has clinical symptoms ambiguously which is leading to late detection and poor prognosis. Currently, there are many imaging methods use for the early detection, diagnosis of pancreatic tumors. Endoscopic ultrasound (EUS) with strength a high-frequency probe, approaching directly pancreas improving tumor, especially small lesions < 2 cm. This study wa...

Different types of benign or malignant cystic lesions can be observed in the pancreas. Pancreatic cystic lesions are classified under pathology terms into simple retention cysts, pseudocysts and cystic neoplasms. Mucinous cystic neoplasm is a frequent type of cystic neoplasm and has a malignant potential. Serous cystadenoma follows in frequency and is usually benign. Intraductal papillary mucin...

BACKGROUND Previous studies have demonstrated that endoscopic ultrasound-fine needle aspiration (EUS-FNA) is a reliable tool for diagnosing pancreatic lesions; however, the reported sensitivity and specificity vary greatly across studies. The aim of this study was to pool the existing literature and assess the overall performance of EUS-FNA in the diagnosis of solid pancreatic lesions. METHOD...

Pancreatic cancer is one of the most malignant types of tumor. It is important to elucidate the underlying molecular mechanisms of pancreatic tumorigenesis and to identify novel biomarkers as therapeutic targets of pancreatic cancer. In the present study, the protein expression levels of Wnt inhibitory factor 1 (WIF1) and receptor tyrosine kinase-like orphan receptor 2 (ROR2) were examined in a...

For curative resection of pancreatic endocrine tumours, minimally invasive methods of pancreatic surgery, such as laparoscopy, should be indicated only for benign tumours. Among these uncommon tumours, pancreatic insulinomas are mostly benign and solitary. Successful management of patients with insulinomas relies on accurate localization of the tumour and the use of appropriate surgical techniq...

CONTEXT Chronic inflammatory vasculitis, namely Wegener's granulomatosis, is an autoimmune disease predominantly affecting the respiratory tract and rarely the mucosa of the upper or lower gastrointestinal tract. We report two cases of isolated pancreatic manifestation of Wegener's granulomatosis, mimicking a tumor. CASE REPORTS Two patients, a 57-year-old man and a 68-year-old woman, present...

Copyright: © 2012 Williamson JB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Pancreatic cysts are being discovered with increasing frequency due to the expanding use of cross-sectional imaging. The ...

PURPOSE Recent microarray analyses revealed that expression of S100A11 is up-regulated in pancreatic cancer. The aim of the present study was to evaluate the association of S100A11 with pancreatic carcinogenesis. EXPERIMENTAL DESIGN We measured S100A11 mRNA expression in various clinical samples related to pancreatic cancer and its precursor lesions, intraductal papillary mucinous neoplasm (I...