Focal acral hyperkeratosis (FAH) is a rare genodermatosis. FAH usually observed in the second or third decades of life, and it type palmoplantar keratoderma, heterogeneous group diseases characterized by abnormal incrassation palms soles. Although an autosomal dominant inher- itance, could also be sporadic. It known as variant Costa’s Acrokeratoelastoidosis (AKE). Its etiology not clearly there...

Palmoplantar psoriasis (PPP) presents with typical scaly patches sometimes studded with sterile pustules. It is chronic and recalcitrant to therapy; it often causes itching, burning, painful ragades and can lead to severe disabilities (1). Some preliminary works (2-4) have established that an excimer laser-generated 308 nm UVB radiation is effective in the treatment of psoriasis. In our study, ...

espanolLa pitiriasis rubra pilaris es una dermatosis infrecuente cuya etiologia se desconoce; caracteriza por papulas foliculares hiperqueratosicas, placas eritematosas y escamosas que pueden progresar a eritrodermia, con islas de piel sana, queratodermia palmoplantar. Los subtipos III, IV V, segun la clasificacion Griffiths, observan exclusivamente en ninos. El tratamiento esta constituye un d...

Naxos disease is a recessively inherited arrhythmogenic right ventricular cardiomyopathy in which the cardiac phenotype is associated with palmoplantar keratoderma and woolly hair. The hair phenotype is unique, characterized by congenital woolly, curly, rough, and light-colored scalp hair and sparse eyebrows. However, arrhythmias and severe cardiomyopathies are causes of severe life threatened ...

Pachyonychia congenita (PC) is a rare autosomal dominant genodermatosis characterized by hyperkeratosis affecting the nails and palmoplantar areas, oral leucokeratosis, and cystic lesions. It is classically subdivided into two major variants, PC-1 (Jadassohn-Lewandowski syndrome) and PC-2 (Jackson-Lawler syndrome), according to the localization of the mutations in the KRT6A/KRT16 or KRT6B/KRT17...

Sir, Abnormal keratinization of the distal part of the hair follicle can prevent emergence of the growing hair from the follicle and lead to spiral growth within a hyperkeratotic papule, socalled ``rolled hairs'' (1). Rolled hairs have been reported in patients with keratosis pilaris (1), neurodermatitis (1), palmoplantar keratoderma (2), and hypertrichosis (3). The disorder has also been assoc...

HIV/syphilis co-infection is common because both conditions affect similar risk groups. HIV interferes with the natural history of syphilis, which often has atypical clinical features and nervous system involvement in the early stage of disease. We report the case of an HIV-positive patient with secondary syphilis, scaling palmoplantar keratoderma, scrotal eczema, balanitis and urethritis mimic...