In this work, we discuss the preliminary results of the effectiveness of the hemorrhoidal artery ligation under control Doppler as a new technique for the treatment of hemorrhoids. We report the results of patients with hemorrhoids we have followed over a period of one year who were treated with HAL Doppler. The intra-and postoperative complications were monitored. Patient follow-up was establi...

BACKGROUND Pancreatic diseases such as cancer, idiopathic recurrent pancreatitis, and chronic pancreatitis, can cause pain that is difficult to control. Pain is one of the most debilitating symptoms and demands increasing doses of analgesics and narcotics, as well as the number of hospital admissions, with a direct implication in the costs of medical treatments. OBJECTIVE To describe the expe...

Vioxx is a cyclooxygenase (COX)-2 selective, non-steroidal anti-inflammatory drug (NSAID) that was approved by the USA’s Food and Drug Administration (FDA) in May 1999 for the relief of the signs and symptoms of osteoarthritis, the management of acute pain in adults, and the treatment of menstrual symptoms. Vioxx was later also approved for the relief of signs and symptoms of rheumatoid arthrit...

Pharmaceuticals have emerged as a major group of environmental contaminants over the past decade but relatively little is known about their occurrence in freshwaters compared to other pollutants. We present a global-scale analysis of the presence of 203 pharmaceuticals across 41 countries and show that contamination is extensive due to widespread consumption and subsequent disposal to rivers. T...

BACKGROUND Alcohol use and illicit drug use peak during young adulthood (around 18-29 years of age), but comparatively little is known about polydrug use in nationally representative samples of young adults. Drawing on a nationally representative cross-sectional survey (Australian National Drug Strategy Household Survey), this study examines polydrug use patterns and associated psychosocial ris...

Our aim is to assess the quality-of-life (QoL) of cancer patients and the effect of sociodemographic characteristics, medical history, and disease management, on QoL. The present study included 318 cancer patients. The most common diagnosis in this study were breast cancer (30.0%) and gastrointestinal cancer (27.7%). A form exploring sociodemographic variables and the EORTC QLQ-C30 questionnair...

Textile materials, as a suitable matrix for different active substances facilitating their gradual release, can have an important role in skin topical or transdermal therapy. Characterized by compositional and structural variety, those materials readily meet the requirements applications specific therapies. Aromatherapy, antimicrobial painkillers, hormone therapy, psoriasis treatment, atopic de...

Kidney stone disease is a crystal concretion formed generally within the kidneys. It an accumulative urological disorder of human health, affecting about 12% world population. Higher risk kidney failure which has been associated with end stage renal failure. Calcium oxalate, forms at Randall's plaque on papillary surfaces, most common type stone. Stone formation highly prevalent, rates up to 14...

Background and Purpose New remedies are required for the treatment of neuropathic pain due to insufficient efficacy available therapies. This study provides a novel approach develop painkillers chronic treatment. Experimental Approach The rat formalin test spinal nerve ligation model were used evaluate antinociception protopanaxadiol. Primary cell cultures, immunofluorescence staining, gene pro...

BACKGROUND Fibromyalgia (FM) is characterized by chronic widespread pain, which is often refractory to conventional painkillers. Numerous clinical studies have demonstrated that antidepressants are effective in treating FM pain. We previously established a mouse model of FM-like pain, induced by intermittent cold stress (ICS). RESULTS In this study, we find that ICS exposure causes a transien...