gabapentin seems to be a safe and well tolerated medication for treating heroine dependence. this study examined the efficacy of gabapentin for relieving withdrawal-related pain due to heroin use.sixty men were recruited from an inpatient psychiatric ward of fatemieh hospital in semnan and randomized to receive either placebo (n = 30) or gabapentin (1800 mg/day) (n = 30) for 7 days. subjective ...

Gabapentin seems to be a safe and well tolerated medication for treating heroine dependence. This study examined the efficacy of gabapentin for relieving withdrawal-related pain due to heroin use.Sixty men were recruited from an inpatient psychiatric ward of Fatemieh hospital in Semnan and randomized to receive either placebo (n = 30) or gabapentin (1800 mg/day) (n = 30) for 7 days. Subjective ...

Objective To compare post-operative pain relieving effect of topical diclofenac 0.1% versus ketorolac 0.5% in Corneal Collagen Cross Linking (CXL) for patients diagnosed with keratoconus. Methods This randomized controlled trial was carried out for six months from October 2016 to March 2017. We included young patients having keratoconus with k-readings greater than 47D and central corneal thi...

OBJECTIVE To study the efficacy of lamotrigine in relieving the pain associated with diabetic neuropathy. METHODS The authors randomly assigned 59 patients to receive either lamotrigine (titrated from 25 to 400 mg/day) or placebo over a 6-week period. Primary outcome measure was self-recording of pain intensity twice daily with a 0 to 10 numerical pain scale (NPS). Secondary efficacy measures...

Ketamine is a dissociative anesthetic agent that has been widely used in surgery and for relieving pain in chronic cancer patients. We applied ketamine to breast cancer cell line MDA-MB-231 to detect the effect of treatment and molecular mechanisms involved. We found that ketamine can upregulate the level of anti-apoptosis protein Bcl-2, which promotes breast cancer cell invasion and proliferat...

As many as one in five Americans lives with chronic pain.[1] Many of these people suffer from neuropathic pain (nerve‐related pain) ‐‐ a condition that is associated with numerous diseases, including diabetes, cancer, multiple sclerosis, and HIV. In most cases, the use of standard analgesic medications such as opiates and NSAIDS (non‐steroidal anti‐ inflammatory drugs) is ineffective at relievi...

As many as one in five Americans lives with chronic pain.[1] Many of these people suffer from neuropathic pain (nerve‐related pain) ‐‐ a condition that is associated with numerous diseases, including diabetes, cancer, multiple sclerosis, and HIV. In most cases, the use of standard analgesic medications such as opiates and NSAIDS (non‐steroidal anti‐ inflammatory drugs) is ineffective at relievi...

BACKGROUND Persistent pain is a common problem for older people. Knowledge about how nursing and paramedical staff perceive these people and what they do to relieve the pain seems scarce. AIM To explore nursing and paramedical staff perceptions of older people in persistent pain and their day-to-day management of pain. METHODS Interviews in Swedish with 52 nursing auxiliaries, Registered Nu...