A new inhalation synchronised dosimeter triggered by low inspiratory flow rates has been assessed. The methacholine challenge test using dosimeter nebulisation with controlled tidal breathing was compared with continuous nebulisation using De Vilbiss No 40 nebulisers with deep inhalations in 11 asthmatic subjects. Within subject PD20 FEV1 values were lower with the dosimeter method than with th...

A quantitative comparison of two full three-dimensional (3D) gel dosimetry techniques was assessed in a clinical setting: radiochromic gel dosimetry with an in-house developed optical laser CT scanner and polymer gel dosimetry with magnetic resonance imaging (MRI). To benchmark both gel dosimeters, they were exposed to a 6 MV photon beam and the depth dose was compared against a diamond detecto...

BACKGROUND Application of less toxic normoxic polymer gel of N-isopropyl acrylamide (NIPAM) for radiation therapy has been studied in recent years. AIM In the current study the optical and NMR properties of NIPAM were studied for radiation therapy dosimetry application. MATERIALS AND METHODS NIPAM normoxic polymer gel was prepared and irradiated by 9 MV photon beam of a medical linac. The o...

Introduction: The purpose of this work was to study the ability of MRI normoxic polymer gel dosimetry for evaluating the dose distribution in HDR brachytherapy of esophagial cancer at Imam Reza brachytherapy center (Mashhad, Iran). Materials and Methods: Initially, 2liters of normoxic gel (MAGIC) was fabricated and then poured into 12 calibration test tubes and placed in a perspex walled phanto...

Introduction: External radiotherapy is the most common method of radiotherapy which the most important problem associated with is that there is no difference between healthy and tumor tissues in dose absorption. One way to differentiate the dose sensitivity is to use metal-based nanoparticles. Bismuth oxide nanoparticles are good candidates for cancer radiotherapy. In this study, we investigate...