SCH527123 is a novel, selective CXC chemokine receptor 2 antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia, such as chronic obstructive pulmonary disease. The purpose of this proof-of-principle study was to determine whether SCH527123 i...

OBJECTIVE To evaluate the antibacterial activity of gaseous ozone and chlorhexidine solution on a tooth cavity model. STUDY DESIGN Twenty-one human molars were divided into 3 groups. Cavities were then cut into the teeth (4 per tooth, 28 cavities per group). After sterilization, the teeth were left in broth cultures of 106 colony-forming units (CFU) ml-1 of Streptococcus mutans (S. mutans) at...

As part of a program to reduce electrical energy consumption in the refining process, the effects of the ozone and alkaline peroxide treatments on fibre and handsheet properties, prior and subsequent to low consistency (LC) refining, were assessed and compared by applying different levels of ozone and a range of peroxide and alkali charges to a primary stage hemlock thermomechanical pulp (TMP)....

BACKGROUND The treatment options for oral lichen planus (OLP) are numerous and include topical and systemic agents. Intralesional and systemic corticosteroids are used; however, the therapeutic results are often disappointing. OBJECTIVE To compare the influence of ozone, laser, and topical corticosteroid therapies in the treatment of OLP. METHODS One hundred twenty adult patients with ≤3 cm...

Ozone was found to inhibit oxidative phosphorylation and oxygen uptake in mitochondria of tobacco leaves (Nicotiana tabacum, L. var. White Gold). The inhibition appeared to occur at both substrate and electron-transport chain levels. The inhibition increased with the length of exposure to ozone, however, the phosphorylative system was more sensitive to ozone than the respiratory system. With mi...

Exposure to ozone, which is a major component of air pollution, induces a form of asthma that occurs in the absence of adaptive immunity. Although ozone-induced asthma is characterized by airway neutrophilia, and not eosinophilia, it is nevertheless associated with airway hyperreactivity (AHR), which is a cardinal feature of asthma. Because AHR induced by allergens requires the presence of natu...

Wastewater disinfection by ozone was investigated at pilot and full scale on different wastewater effluents and two types of ozone reactors. It was demonstrated that water quality and, in particular, suspended solids and organic content strongly influence the required ozone dose for a given level of disinfection. The increase in contact time and residual ozone concentration did not improve the ...

The indoor air quality is much more matter of concern as relative to ambient or outdoor air quality, especially in the context of human health.  However, very few studies have been reported for remediation of indoor ozone by plant species. The main objective of this study is to evaluate ozone deposition velocities and ozone removal effectiveness of three indoor ornamental plant species (Dra...

The catalytic decomposition of ozone (200–1600 ppm) to molecular oxygen was investigated over activated carbons in the form of woven fibre fabrics (ACF) or granules (ACG) at room temperature. The dynamics of carbon activity was characterised by two distinct regions. First the ‘‘high activity’’ towards ozone decomposition was observed, which was mainly due to chemical interaction of ozone with c...

The aim of this study was to examine the effect of ozone gas on the remaining bacteria after chemomechanical instrumentation of tooth root canal. The study was carried out at the Department of Endodontics and Restorative dentistry, School of Dental Medicine, University of Zagreb. A total of 37 tooth root canals from 23 teeth (10 incisors, 2 canines, 8 premolars and 3 molars) with a diagnosis of...