نتایج جستجو برای: oxidative stressof

تعداد نتایج: 128196  

Journal: :iranian red crescent medical journal 0
halil beydilli department of emergency medicine, school of medicine, mugla sitki kocman university, mugla, turkey; department of emergency medicine, school of medicine, mugla sitki kocman university, mugla, turkey. tel: +90-2522114835 nigar yilmaz department of medical biochemistry, school of medicine, mugla sitki kocman university, mugla, turkey esin sakalli cetin department of medical biology, school of medicine, mugla sitki kocman university, mugla, turkey yasar topal department of pediatrics, school of medicine, mugla sitki kocman university, mugla, turkey ozgur ilhan celik department of medical pathology, school of medicine, mugla sitki kocman university, mugla, turkey cem sahin department of internal medicine, school of medicine, mugla sitki kocman university, mugla, turkey

conclusions the di was found to induce liver damage by oxidative stress mechanisms. silibinin reduced the oxidative stress by inducing antioxidant mechanisms, thereby showing protective effect against di induced liver damage. further studies with silibinin should be performed regarding di toxicity. materials and methods thirty two wistar albino rats were divided into four groups, as follows: 1)...

Journal: :avicenna journal of phytomedicine 0
akbar anaeigoudari department of physiology, school of medicine, jiroft university of medical sciences, jiroft, iran mahmoud hosseini neurogenic inflammation research center & department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran reza karami student research committee, school of medicine, mashhad university of medical sciences, mashhad, iran farzaneh vafaee neurogenic inflammation research center & department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran toktam mohammadpour student research committee, school of medicine, mashhad university of medical sciences, mashhad, iran ahmad ghorbani pharmacological research center of medicinal plants, school of medicine, mashhad university of medical sciences, mashhad, iran

objective: in the present work, the effects of different fractions of coriandrum sativum (c. sativum), on pentylenetetrazole (ptz)-induced seizures and brain tissues oxidative damage were investigated in rats. materials and methods: the rats were divided into the following groups: (1) vehicle, (2) ptz (90 mg/kg), (3) water fraction (wf) of c. sativum (25 and 100 mg/kg), (4) n-butanol fraction (...

Journal: :avicenna journal of phytomedicine 0
leila safaeian department of pharmacology and toxicology and isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran shaghayegh haghjoo javanmard applied physiology research center, isfahan university of medical sciences, isfahan, iran mustafa ghanadian department of pharmacognosy, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran sima seifabadi department of pharmacology and toxicology and isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran

objective: echium amoenum fisch. & c.a. mey. is used for the treatment of various diseases in traditional medicine. this plant is a major source of anthocyanins with beneficial cardiovascular properties such as anti-atherosclerotic and antihypertensive effects. in the present study, the protective and antioxidant effects of anthocyanin-rich e. amoenum extract were evaluated on human vascular en...

Journal: :international journal of aquatic biology 0
mahdi banaee aquaculture department, natural resource faculty, behbahan khatam alanbia university of technology, iran. milad mehrpak aquaculture department, natural resource faculty, behbahan khatam alanbia university of technology, iran. behzad behzad nematdoost hagi aquaculture department, natural resource faculty, behbahan khatam alanbia university of technology, iran. ahmad noori department of aquaculture, faculty of marine science and technology, hormozgan university, bandar abbas, iran.

the aim of this study was to investigate the effects of administering antioxidants, including vitamin c and chitosan on oxidative stress markers in muscle as edible tissues of cyprinus carpio exposed to cadmium chloride. in this experiment, by exposing to 0.2 mg/l cadmium chloride for 21 days, fish were fed a normal diet, diet containing chitosan (1000 mg/kg diet), vitamin c (1000 mg/kg diet) o...

Journal: :journal of pharmaceutical care 0
arezoo ahmadi anesthesiology and intensive care department, school of medicine, tehran university of medical sciences, tehran, iran. mojtaba mojtahedzadeh clinical pharmacy department, faculty of pharmacy, tehran university of medical sciences, tehran, iran. farzaneh javadi clinical pharmacy department, faculty of pharmacy, islamic azad university of medical sciences, tehran, iran. mohammad abdollahi faculty of pharmacy, and pharmaceutical sciences research centre, tehran university of medical sciences, tehran, iran. atabak najafi anesthesiology and intensive care department, school of medicine, tehran university of medical sciences, tehran, iran. sarah mousavi clinical pharmacy department, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

background: an increased oxidative stress in patients under treatment with high concentrations of oxygen (hyperoxia) is considered to be one of the major mechanisms of lung injury. between different mediators, transition metal ions especially iron, by generation of very reactive free radicals play an important role in oxidative stress process. disruption of normal iron hemostasis has been repor...

Journal: :journal of pharmaceutical care 0
zeliha selamoglu-talas department of biology, faculty of arts and sciences, nigde university, nigde, 51200 turkey ilknur ozdemir department of chemistry, faculty of arts and sciences, inonu university, malatya, 44280 turkey osman ciftci department of pharmaceutical toxicology, faculty of pharmacy, inonu university, malatya, 44280 turkey oguz cakir department of chemistry, faculty of arts and sciences, dicle university, diyarbakir, turkey

background: the blocking of nitric oxide synthase (nos) activity may reason vasoconstriction with formation of reactive oxygen species. propolis has biological and pharmacological properties, such as antioxidant. the aim of this study was to examine the antioxidant effects of propolis which natural product on biochemical parameters in brain and lung tissues of acute nitric oxide synthase inhibi...

Journal: :iranian journal of parasitology 0
hadi samadieh dept. of clinical sciences, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran gholam-reza mohammadi dept. of clinical sciences, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran mohsen maleki dept. of pathobiology, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran hassan borji dept. of pathobiology, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran mohammad azizzadeh dept. of clinical sciences, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran mohammad heidarpour dept. of clinical sciences, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran

background: the aim of this study was to investigate the role of oxidative stress in the pathology of ovine dicrocoeliasis. methods : during dec 2013 - oct 2014, seventy-two sheep (1-3 years) with liver dicrocoeliasis along with 47 healthy sheep were selected from animals admitted for slaughtering at slaughterhouse located in neyshabour, razavi khorasan province, iran. results : in comparison t...

Journal: :research in pharmaceutical sciences 0
b. naghibi t. ghafghazi v. hajhashemi a. talebi d. taheri

the aim of this study was to investigate the protective role of vitamin e against vancomycin-induced nephrotoxicity. there are some evidences that oxidative injury could be involved in its pathogenesis. vitamin e at doses of 50, 100 and 200 mg/kg were administered s.c. to rats 30 min prior to i.p. injection of 200 mg/kg vancomycin (van). drug administrations were done every 12 h for 7 days. aft...

Journal: :iranian biomedical journal 0
محمد تقی محمدی mohammad taghi mohammadi رضا امینی reza amini زهرا جهانبخش zahra jahanbakhsh شهناز شکرفروش shahnaz shekarforoush

background: it is well known that the development of brain oxidative stress is one of the most serious complications of arterial hypertension that evokes brain tissue damage. the aim of this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (htn) rats. methods: experiments were performed...

Journal: :iranian biomedical journal 0
محمد علی میرشکار mohammadali mirshekar مهرداد روغنی mehrdad roghani محسن خلیلی mohsen khalili توراندخت بلوچ نژاد مجرد tourandokht baluchnejadmojarad سعیده عرب موذن saiedeh arab moazzen

background: diabetes mellitus in some clinical cases is accompanied with hyperalgesia. in this study, we evaluated the possible beneficial effect of chronic pelargonidin (pg) treatment on hyperalgesia in streptozotocin (stz)-diabetic neuropathic rat. methods: male wistar rats (n = 56) were divided into seven groups, i.e. control, diabetic, pg-treated control, pg (single- and multiple-dose)-trea...

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