Objective: To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs (AEDs) (gabapentin, lamotrigine, topiramate, tiagabine, oxcarbazepine, levetiracetam, and zonisamide—reviewed in the order in which these agents received approval by the US Food and Drug Administration) in the treatment of children and adults with newly diagnosed partial and gener...

Objective: To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs (AEDs) (gabapentin, lamotrigine, topiramate, tiagabine, oxcarbazepine, levetiracetam, and zonisamide) in the treatment of children and adults with refractory partial and generalized epilepsies. Methods: A 23-member committee including general neurologists, pediatric neurologists, ...

CLINICAL CASE A case is presented of a patient who developed skin lesions on the legs and a bilateral anterior uveitis after taking Oxcarbazepine (Trileptal). DISCUSSION The presence of uveitis in the context of an allergic reaction to an anticonvulsant is a very uncommon and can affect the internal organs. For this reason, it should be taken into account when carrying out a full assessment o...