Canine babesiosis caused by the intraerythrocytic protozoan parasite Babesia canis is a tick-borne disease characterized by a host response that involves both cellular and humoral immunity. This study focuses on the secretion of cytokines Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Keratinocyte Chemotactic-like (KC-like), Interleukins (IL)-2, IL-7, IL-8, IL-10, IL-15, IL-18 and M...

progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. 5. WHO hospital discharge and follow-up policy for patients who have been diagnosed with severe acute respiratory syndrome (SARS) [monograph on the Internet]. To the Editor: Human babesiosis, caused by Babesia microti, was initially described in the eastern United States in 1970 in ...

As large animal models continue to play an important role in translating lung-directed therapeutic strategies from laboratory animals to humans, there is an increasing interest in the analysis of endogenous regulators of inflammation at both a genomic and a therapeutic level. To this end, we have sought to characterize the ovine ortholog of elafin, an important regulator of inflammation in huma...

BACKGROUND Dirofilaria repens is a mosquito-transmitted, filarial nematode parasitizing dogs, cats and other carnivores. Recently, this parasite has spread in central Europe, including Poland. The aim of the present study was to estimate the prevalence of D. repens in cats and dogs in different regions of the country and to investigate the occurrence and consequences of co-infection with anothe...

Figure 1. Wright Giemsa-stained thin prep peripheral blood smears (original magnification, ϫ1000) demonstrating appliqué (B) and headphone (C) morphologies, which are characteristic of Plasmodium falciparum, and extracellular ring forms (D), which are characteristic of Babesia microti. Diagnosis: Babesiosis due to Babesia microti infection from a tick bite. Peripheral blood smear from the state...

BACKGROUND Babesiosis is an emerging, tick-borne zoonosis caused by intraerythrocytic protozoa of the genus Babesia. Babesia microti is the main pathogen causing human disease and is endemic in the northeastern and upper midwestern parts of the USA. Severity of infection ranges from mild, self-limited, febrile viral-like illness accompanied by nonspecific symptoms to life-threatening infection ...

Aim The present research work was undertaken to describe various clinical signs and hematobiochemical alterations in dogs affected with Babesia gibsoni. Materials and Methods Blood smears from a total of 79 suspected dogs of Anand region as well as Surat region of Gujarat state (India) were screened for detection of intraerythrocytic piroplasm of small form of Babesia. Diagnosis was made on t...

A novel photoactivatable analog of ovine corticotropin-releasing factor (ovine photoCRF) has been synthesized and characterized. A diazirine group, the 4-(1-azi-2,2,2-trifluoroethyl)benzoyl residue, was covalently bound to the amino terminus of ovine CRF (oCRF), which was N-terminally extended by a tyrosyl residue for radioactive labeling with 125I. Under mild conditions, photolysis yielded hig...