BACKGROUND In New York City (NYC), the annual mortality rate is higher for accidental drug overdoses than for homicides; cocaine and opiates are the drugs most frequently associated with drug overdose deaths. We assessed trends and correlates of cocaine- and opiate-related overdose deaths in NYC during 1990-2000. METHODS Data were collected from the NYC Office of the Chief Medical Examiner (O...

STUDY OBJECTIVE Emergency physicians have an opportunity to provide overdose fatality prevention interventions to individuals at risk for experiencing or witnessing an overdose to reduce fatality. The present study uses data about the most recent overdose observed by a sample of inner-city drug users to determine the circumstances of overdose that are associated with overdose fatality. METHOD...

Amlodepine poisioning is rare. Amlodepine toxicity presents as hypotension, pulmonary oedema both cardiogenic and non-cardiogenic. Standard approaches to the management of calcium channel blocker overdoses, including fluid resuscitation, gut decontamination, administration of calcium, as well as supportive care, are often ineffective. pWe report a case of amlodepine poisioning with acute respir...

A 37-year-old woman experienced a witnessed generalized seizure in the Emergency Department three hours after ingesting approximately 1400 mg of fluoxetine in a suicide attempt. Although the majority of fluoxetine ingestions are benign, seizures may occur after large intentional overdoses.