نتایج جستجو برای: overall suitability index osi
تعداد نتایج: 854214 فیلتر نتایج به سال:
In this chapter we give the motivation and basic concepts of the OSI reference model, discuss its seven-layer architecture, the communication between systems using the OSI model, and finally the relationship between the OSI model and multilayer switching.
Land suitability evaluation is the fitness of a given tract of land based on its production potential for a defined use. This study was conducted to evaluate the land suitability of Mobarakeh-Zarrinshahr district located in west of Isfahan province using Analytical Hierarchy Process (AHP) technique. To do the evaluation, firstly the hierarchy structure was established, which consisted of object...
The aim of this study was to determine oxidative stress caused by mercury chloride (HgCl2) in rainbow trout (Oncorhynchus mykiss) liver tissue. For purpose, the LD50 value HgCl2 on determined as 551 μg/L. In study, 40 fish four groups were exposed 25% and 50% (138 276 µg/L) two subletal doses for 2 7 days, with 10 (n=10) each group. To stress; peroxynitrite (ONOO−), total oxidant level (TOS), a...
Agents targeting insulin-like growth factor 1 receptor (IGF-1R) are being actively examined in clinical trials. Although there has been some initial success of single-agent targeting IGF-1R, attempts in later studies failed because of resistance. This study aimed to understand the effects of programmed cell death 4 (Pdcd4) on the chemosensitivity of the IGF-1R inhibitor OSI-906 in colorectal ca...
The phosphoinositide 3-kinase (PI3K)/AKT/mTOR pathway is frequently activated in human cancers, and mTOR is a clinically validated target. mTOR forms two distinct multiprotein complexes, mTORC1 and mTORC2, which regulate cell growth, metabolism, proliferation, and survival. Rapamycin and its analogues partially inhibit mTOR through allosteric binding to mTORC1, but not mTORC2, and have shown cl...
PURPOSE To study the role of drug transporters in central nervous system (CNS) penetration and cellular accumulation of erlotinib and its metabolite, OSI-420. EXPERIMENTAL DESIGN After oral erlotinib administration to wild-type and ATP-binding cassette (ABC) transporter-knockout mice (Mdr1a/b(-/-), Abcg2(-/-), Mdr1a/b(-/-)Abcg2(-/-), and Abcc4(-/-)), plasma was collected and brain extracellul...
Citation: Puckett BJ, Theuerkauf SJ, Eggleston DB, Guajardo R, Hardy C, Gao J and Luettich RA (2018) Integrating Larval Dispersal, Permitting, and Logistical Factors Within a Validated Habitat Suitability Index for Oyster Restoration. Front. Mar. Sci. 5:76. doi: 10.3389/fmars.2018.00076 Integrating Larval Dispersal, Permitting, and Logistical Factors Within a Validated Habitat Suitability Index...
Background: Multiple organ dysfunctions have been linked to exposure to polycyclic aromatic hydrocarbons (PAH) and oxidative stress (OS), oxidative DNA damage, and inflammatory response to PAH have been implicated. The biomarkers of OS (malondialdehyde (MDA), total plasma peroxide (TPP), total antioxidant capacity (TAC), glutathione (GSH), nitric oxide (NO), oxidative stress index (OSI)); 8-hy...
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