BACKGROUND Hyperimmunoglobulin E (hyper-IgE) syndrome is a rare immunodeficiency characterised by recurrent skin and respiratory tract infections, skeletal and dental abnormalities, chronic eczema, and elevated serum IgE. We describe a family with four hyper-IgE syndrome patients (38, 37, 30 and 7 years old), in which we investigated the cytokine response to both specific and non-specific stimu...

background: the prevalence of polycystic ovarian syndrome (pcos) particularly is increased in adolescents. very few longitudinal follow-up for assessment of ovarian reserve in women of late reproductive age with previously confirmed pcos have been conducted, especially after its diagnosis and treatment in adolescence. objective: the aim of the present study was to compare of the ovarian reserve...

Background: To compare the effect of GnRH agonist administration with vaginal progesterone on serum progesterone in Luteal phase in control ovarian hyper stimulation and intrauterine insemination cycles Materials and Methods: In this clinical trial, 242 infertile patients because of UEI (unexplained inferetility candidate for ovarian stimulation and intrauterine insemination reffering to infert...

Introduction: Any circumstance that alters the balance of oestrogen and progesterone leads to excessive, prolonged estrogenic stimulation, or preventing counteracting effects causing various pathological conditions in reproductive system, as a result. Women with polycystic ovarian syndrome (PCOS) have mostly anovulatory cycles low serum levels. Endometrial hyperplasia is most often due excess w...

Background: Ovarian hyperstimulation syndrome is the most serious complication of ovarian stimulation. This novel study aimed to describe an outpatient treatment protocol for ovarian hyperstimulation syndrome (OHSS) that results in rapid normalization of symptoms with minimal side effects. Materials and Methods: A prospective study was undertaken at Infertility department of Shariati Hospital a...

BACKGROUND The identification of polymorphisms associated with a disease can help to elucidate its pathogenesis, and this knowledge can be used to improve prognosis for women with a particular disorder, such as polycystic ovary syndrome (PCOS). Since an altered response to ovarian stimulation is also a characteristic of the disease, further knowledge about its aetiology could help in defining t...