OBJECTIVE despite endometriosis being a common disease, where early detection is key to preventing its progression, it is a condition often overlooked in adolescents. The aim of this study was to report the clinical characteristics of adolescent patients with endometriosis monitored in a tertiary hospital. METHODS a retrospective study of 394 patients undergoing surgery with a histological di...

INTRODUCTION Laparoscopy is a long-established diagnostic and therapeutic method for treating women suffering from infertility. The application of this method of treatment can help achieve pregnancy only if there is correct classification of patients and evaluation of their partner's reproductive capacity. The main predictors of achieving pregnancy in a couple treated for infertility are the wo...

Endometriosis-associated ovarian cancer (EAOC) is an evolving clinical entity believed to develop from endometriosis. Continuous efforts are nowadays invested in exploring its pathogenesis and causality. Since endometrioma a widespread sub-type of the disease, malignant transformation EAOC during reproductive age may cause much concern affect management. The summary relative risk developing wom...

On the roles of skin type and sun exposure in the risk of endometriosis and melanoma The recent paper by Kvaskoff et al. 1 reported observations of endometriosis risk in relation to naevi, freckles and skin sensitivity to sun exposure. The study found significantly increased risk for endome-triosis for those highly sensitive to sun exposure and for those with naevi or freckles. Those with dark ...

Rectovaginal Endometriosis (RVE) is a severe form of endometriosis classified by Kirtner as stage 4 [1,2]. It is less frequent than peritoneal or ovarian endometriosis affecting 3.8% to 37% of patients with endometriosis [3,4]. RVE infiltrates the rectum, vagina, and rectovaginal septum, up to obliteration of the pouch of Douglas [4]. Endometriotic nodules exceeding 30 mm in diameter have 17.9%...

Because ovarian function is necessary for the development and maintenance endometrial implants, endometriosis has been reported only in the reproductive ages and so, is normally not seen before age 15 or after menopause. Endometriosis is most common in women between the ages of 25 and 35. However, after menopause, there are two factors which may promote or maintain endometriosis. One is the use...

we report a case of florid polypoid endometriosis presenting with advanced bulky disease in pelvis with serum ca – 125 levels of 7844u/ml. the extent of tumor, ct scan findings, elevated serum ca – 125 levels were suggestive of ovarian malignancy. histopathology demonstrated endometrial glands and stroma. glands were neither crowded nor complex and were separated by a fibromatous stroma that co...

BACKGROUND Although nerve fibres are present in eutopic and ectopic endometrium, it is unclear whether they appear in ovarian endometriotic lesions. We investigated the presence of nerve fibres in ovarian endometriotic lesions and its correlation with clinical parameters in women with ovarian endometriosis. METHODS Histological sections of ovarian endometriotic lesions from 61 women with ovar...

Endometriosis is a common monoclonal benign proliferative disorder that may give rise to pelvic malignancy. Epithelial ovarian carcinoma is responsible for a large proportion of gynaecological cancer-associated deaths. Early diagnosis is difficult and screening is generally unsuccessful. Knowledge of the risk factors for the development of endometriosis and progression to malignancy may assist ...

OBJECTIVE There is an increased risk of developing ovarian cancer (OC) in patients with endometriosis. Hence, development of new biomarkers may provide a positive clinical outcome for early detection. MicroRNAs (miRNAs) are small non-coding RNAs that play an important role in biological and pathological process and are currently used as diagnostic and prognostic markers in various cancers. In t...