background and objective: obstructive sleep apnea (osa) is a disease with serious consequences. many portable devices have been developed to overwhelm some of limitations in the accessibility of the gold standard test for osa, polysomnography (psg). this study aimed to determine diagnostic accuracy of a portable sleep apnea screener against psg in patients of a sleep clinic. materials and metho...

We give several equivalent combinatorial descriptions of the space of states for the box-ball systems, and connect certain partition functions for these models with the q-weight multiplicities of the tensor product of the fundamental representations of the Lie algebra gl(n). As an application, we give an elementary proof of the special case t = 1 of the Haglund–Haiman–Loehr formula. Also, we pr...

ions and first-class procedures We've seen two ways to express the square-root computation as an instance of a more general method, once as a fixed-point search and once using Newton's method. Since Newton's method was itself expressed as a fixed-point process, we actually saw two ways to compute square roots as fixed points. Each method begins with a function and finds a fixed point of some tr...

Growth in an adjacent market is tougher than it looks; three-quarters of the time, the effort fails. But companies can change those odds dramatically. Results from a five-year study of corporate growth conducted by Bain & Company reveal that adjacency expansion succeeds only when built around strong core businesses that have the potential to become market leaders. And the best place to look for...

Twenty five years after the original epidemiological studies 2 two thirds of all patients with coronary artery disease still die before reaching hospital (p 1065). These patients have no opportunity to benefit from the advances in hospital treatment of acute myocardial infarction, such as thrombolysis, that have dramatically reduced mortality in hospital. It is particularly sobering to see in t...

Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses. In 2007 ZIKV caused an outbreak of relatively mild disease characterized by rash, arthralgia, and conjunctivitis on Yap Island in the southwestern Pacific Ocean. This was the first time that ZIKV was detected outside of Africa and Asia. The history, transmission dynamics, virology, a...

Introduction Cerebral toxoplasmosis is a leading cause of central nervous system (CNS) lesions in severely immunocompromised human immunodeficiency virus+ (HIV+) patients who are seropositive for the parasite and have not received effective chemoprophylaxis. A 48-year-old HIV+ woman presented to our emergency room with seizure and decreased level of consciousness. She had developed fever, produ...