نتایج جستجو برای: otosclerosis
تعداد نتایج: 599 فیلتر نتایج به سال:
Otosclerosis is a common disorder that leads to conductive hearing loss. Most patients with otosclerosis also have tinnitus, and surgical treatment is known to improve hearing as well as tinnitus. Some patients however experience worsening of tinnitus after the operation, but there are no known factors that allow surgeons to predict who will be at risk. In this prospective observational study o...
The etiopathogenesis of otosclerosis is still controversially discussed. The major hypotheses discussed are a viral infection on a genetic background and an (autoimmune) collagen disease. The aim of our study was to investigate by immunohistochemistry the expression pattern of collagens within the otosclerotic focus. Stapes footplates from 30 patients with clinical otosclerosis undergoing stape...
Otosclerosis is a common form of progressive hearing loss, characterized by abnormal bone remodeling in the otic capsule. The etiology of the disease is largely unknown, and both environmental and genetic factors have been implicated. To identify genetic factors involved in otosclerosis, we used a case-control discovery group to complete a genome-wide association (GWA) study with 555,000 single...
Round window (RW) stimulation is a new type of middle ear implant's application for treating patients with middle ear disease, such as otosclerosis. However, clinical outcomes show a substantial degree of variability. One source of variability is the variation in the material properties of the ear components caused by the disease. To investigate the influence of the otosclerosis on the performa...
INTRODUCTION Stapes surgery is mainly used to improve hearing in otosclerosis; however, many patients report alleviation of tinnitus after surgery. OBJECTIVE to evaluate the effectiveness of stapes surgery for improving tinnitus symptoms. MATERIALS AND METHODS This prospective study included 29 patients with surgically proven otosclerosis, who had undergone stapedectomy or stapedotomy. We c...
OBJECTIVES/HYPOTHESIS To prospectively evaluate hearing outcomes in children with otosclerosis undergoing primary stapes surgery. STUDY DESIGN A nonrandomized, nonblinded, prospective case series. METHODS Thirty-four consecutive pediatric patients who underwent 41 primary stapedotomies for otosclerosis in a tertiary referral center were included. Patients were included when there was eviden...
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