A replication error (RER+) phenotype, characterized by somatic instability in simple repeated sequences, is associated with several types of cancer. To determine if a defect in DNA replication fidelity or repair of replication errors might explain this instability, we compared both processes in cell-free extracts from RER+ endometrial and colorectal cancer cell lines to RER- cell lines. SV40 or...

In this study, the effect of repair on fatigue life of tubular joints is investigated. Six cracked specimens precedently subjected to fatigue loading undergone to weld repair. Two of those specimens were shot peened before primary fatigue loading.  It is shown that repair gives rise to about 150% increase in fatigue life for original specimens while the increase of fatigue life for shot-peened ...

Introduction: Endoscopic repair is considered the treatment of choice in cerebrospinal fluid (CSF) rhinorrhea. The aim of our study was to analyze the etiopathogenesis of CSF rhinorrhea, the outcome of treatment and the causes of failure in a developing-country setting.   Materials and Methods: A retrospective review of patients treated with endoscopic repair for CSF rhinorrhea at a tertiary ca...

farm machinery managers often need to make complex economic decisions on machinery replacement. repair and maintenance costs can have significant impacts on this economic decision. the farm manager must be able to predict farm machinery repair and maintenance costs. this study aimed to identify a regression model that can adequately represent the repair and maintenance costs in terms of machine...

the overall goal of this study was to identify the appropriate biomaterials able to facilitate the regeneration in rat's injured adult spinal cord. acute damage to axons is manifested as a breach in their membranes, ionexchange distortion across the compromised region, local depolarization and even conduction block. it would be of particular importance to interrupt the progress of events h...

BACKGROUND Anatomic repair of tendon ruptures is an important goal of surgical treatment. There are limited data on the triceps brachii insertion, footprint, and anatomic reconstruction of the distal triceps tendon. HYPOTHESIS An anatomic repair of distal triceps tendon ruptures more closely imitates the preinjury anatomy and may result in a more durable repair. STUDY DESIGN Descriptive and...

Pediatric neurological disorders including muscular dystrophy, cerebral palsy, and spinal cord injury are defined as a heterogenous group of diseases, of which some are known to be genetic. The two significant features represented for stem cells, leading to distinguish them from other cell types are addressed as below: they can renew themselves besides the ability to differentiate into cells wi...

     The overall goal of this study was to identify the appropriate biomaterials able to facilitate the regeneration in rat's injured adult spinal cord. Acute damage to axons is manifested as a breach in their membranes, ionexchange distortion across the compromised region, local depolarization and even conduction block. It would be of particular importance to interrupt the progress of events h...