Peripheral ossifying fibroma (POF) is a slow growing asymptomatic benign tumor which may induce facial asymmetry. It is an occasional growth of the anterior region of mandible and accounts for 3.1% of all oral tumors and 9.6% of the gingival lesions. About 60% of these tumors occur in maxilla and more than 50% of all cases of maxillary POFs are found in the incisors and canine areas. They are t...

This report contains a statistical review of 559 cases of lesions forming hard tissues that were diagnosed by the departments of Clinical Pathophysiology and of Pathology at Tokyo Dental College from 1966 to 2001. Sixteen kinds of lesions which were related to the formation of bone, cartilage or cementum were analysed: osteoma, osteo-chondroma, chondroma, osteoid osteoma, osteoblastoma, ossifyi...

Various terms have been suggested to describe non-ossifying fibroma including fibrous cortical defect, cortical desmoid, metaphyseal fibrous defect and non-osteogenic fibroma. Regardless of the term used, they probable all refer to abnormal osteoclastogenesis at the metaphyseal region. Non-ossifying fibroma is a benign fibrogenic tumor primarily affecting children and adolescents. It is the mos...

Intraoral ossifying fibromas have been described in the literature since the late 1940s. Peripheral ossifying fibroma (POF) is usually a fibroma of the gingival which shows areas of calcification or ossification. It is a nonneoplastic enlargement of gingiva. Due to its clinical and histopathological similarities, some POFs are believed to develop initially as a pyogenic granuloma that undergoes...

Ossifying fibroma (osteofibrous dysplasia) is a rare fibro-osseous lesion made up of fibrous tissue with woven bone formation. It is most commonly found in the tibia and fibula of children ten years of age or younger. The most important differential diagnosis is monostotic fibrous dysplasia, which is radiologically similar but without woven bone rimmed by active osteoblasts like ossifying fibro...