In this paper, we propose a superpixel classification based optic cup segmentation for glaucoma detection. In the proposed method, each optic disc image is first over-segmented into superpixels. Then mean intensities, center surround statistics and the location features are extracted from each superpixel to classify it as cup or non-cup. The proposed method has been evaluated in one database of...

BACKGROUND Positron emission tomography (PET)-CT is a useful diagnostic adjunct for cancer unknown primary (CUP) of the head and neck; however, the increased cost has not been justified with an economic evaluation in this patient population. METHODS A decision tree analysis was performed from the perspective of the third party payer. Primary outcome was cost per life year gained ($/LYG). The ...

PURPOSE To quantitatively evaluate the change in the optic disc topographic parameters associated with reduction in the intraocular pressure (IOP) after trabeculectomy in adult patients with glaucoma. METHODS A series of 22 patients (mean age: 45.7+/-15.1 years) with several types of glaucoma were examined for various parameters of optic disc before and after trabeculectomy. Cup area, cup-to-...

BACKGROUND Cancer of unknown primary (CUP) accounts for approximately 3% of all malignancies. Avoiding immune destruction is a major cancer characteristic and therapies aimed at immune checkpoint blockade are in use for several specific cancer types. A comprehensive survey of predictive biomarkers to immune checkpoint blockade in CUP were explored in this study. METHODS About 389 cases of CUP...

The stability of cementless acetabular cups depends on a close fit between the components and reamed acetabular cavities to promote bone ingrowth. Cup performance and stability are affected by both design and environmental (patient-dependent and surgical) factors. This study used a statistically based metamodel to determine the relative influences of design and environmental factors on acetabul...

Glaucoma is a chronic eye disease that leads to blindness. This disease cannot be cured but we can detect the disease in time. Current tests using intraocular pressure (IOP) measurement are not sensitive enough for population based glaucoma screening. Optic nerve head assessment in retinal fundus images is more promising and superior than current methods. This paper proposes segmentation of opt...

Cancer of unknown primary sites (CUP) is a compilation of various malignant entities--the majority of which behave aggressively and carry poor prognosis. CUP is classified into two different clinicopathological groups: the unfavourable (poor-prognosis) and the favourable (good-prognosis) group. Patients with favourable subsets are treated relevant to the hidden primary tumour chemotherapy regim...

Glaucoma is a chronic eye disease that leads to vision loss. As it cannot be cured, detecting the disease in time is important. This research proposes optic disc and optic cup segmentation using superpixel classification for glaucoma screening. It uses the 2D fundus images. In optic disc segmentation, clustering algorithms are used to classify each superpixel as disc or nondisc. For optic cup s...