Sir1p is one of four SIR (silent information regulator) proteins required for silencing the cryptic mating-type locus HMRa in the budding yeast Saccharomyces cerevisiae. A Sir1p interaction with Orc1p, the largest subunit of the origin recognition complex (ORC), is critical for Sir1p's ability to bind HMRa and function in the formation of silent chromatin. Here we show that a discrete domain wi...

An organic Rankine cycle (ORC) is a power cycle employing an organic working fluid. The term ORC is also applied generally to any Rankine cycle with a low-grade heat source (80° – 300 o C). Because ORC are often employed in small-scale applications, use of positive displacement equipment is favored over the centrifugal units used in large-scale power plants. A key feature of a positive displace...

The use of the organic Rankine cycle (ORC), flash (OFC) and Kalina (KC) is proposed to enhance electricity generated by a supercritical CO2 recompression Brayton (SCRB) cycle. Novel comparisons SCRB/ORC, SCRB/OFC SCRB/KC integrated plants from thermodynamic, exergoeconomic sustainability perspectives are performed choose most appropriate bottoming for waste heat recovery SCRB For comprehensiven...

PURPOSE To explore the morbidity, mortality and oncological results of laparoscopic radical cystectomy (LRC) in the elderly patients over 75-year-old in contrast with open radical cystectomy (ORC). MATERIALS AND METHODS We analyzed 46 radical cystectomies from January 2009 to December 2013 in patients over 75-year-old in our institute, 21 patients in the LRC group and 25 in the ORC group. Dem...

The main purpose of this research is to analyze the performance of an evaporator for the organic Rankine cycle (ORC) system and discuss the influence of the evaporator on the operating characteristics of diesel engine. A simulation model of fin-and-tube evaporator of the ORC system is established by using Fluent software. Then, the flow and heat transfer characteristics of the exhaust at the ev...

Current software development often relies on non trivial coordination logic for combining autonomous services, eventually running on different platforms. As a rule, however, such a coordination layer is strongly weaved within the application at source code level. Therefore, its precise identification becomes a major methodological (and technical) problem and a challenge to any program understan...

Van der Aalst recently proposed a set of workflow patterns to characterize the kinds of control flow that appear frequently in workflow processes. These patterns are useful for evaluating the capabilities of workflow systems and models. In this paper we provide implementations of the workflow patterns in Orc, a new process calculus for orchestrating wide-area computations. A key feature of the ...