Desmoplastic melanoma(DM) is a subtype of malignant melanoma, and there are very few reports on the occurrence this disease in oral region. Since DM mainly composed achromatic spindleshaped tumor cells, its clinical histopathological diagnoses difficult. However, immunohistochemical staining useful for diagnosis DM.

Back Ground:The most important prognostic factor for squamous cell carcinoma (SCC) of oral is the status cervical lymph nodes. Cure rates drop by 50% with involvement regional nodes.The rate occult metastasis in clinically negative neck tongue cancers ranges from <20% to >30% depending on many predictors. Methods:The relationship clinical and histologic features primary tumor nodes was in...

The aim of our studies is to determine the dynamics of natural killer (NK) cell modulation in gingivae in precancerous and cancerous stages of pancreatic and oral cancers in P48+/Cre;LSL-KRASG12D (KC) mice carrying a pancreas-specific oncogenic Kras mutation and BLT-humanized mice. Wild type and KC mice fed with control diet (CD) or high-fat calorie diet (HFCD), and the pancreatic and oral tumo...

Oral squamous cell carcinoma (OSCC) is one of the most common and deadliest malignancies in head neck region with survival rate ranging between 25%-55%. Epithelial-mesenchymal transition (EMT) plays a major role cancer progression tissue invasion considered to be key process associated recurrence, lymph node metastasis low patients OSCC. Studies have shown that Endothelin-1 (ET-1), potent vasoc...

background and aim: oral mucosal lesions have various prevalence rates among different populations. few studies have evaluated the frequency of oral mucosal lesions in iranian population. this study aimed to determine the frequency of oral mucosal lesions and the related factors.                        materials and methods: this descriptive study was conducted based on the data in the archives...

introduction: leukoplakia is the most common precancerous lesion of the oral mucosa and may range microscopically form benign hyperkeratosis to invasive squamous cell carcinoma. p53 is a tumor suppressor protein; whereas, proliferative cell nuclear antigen (pcna) is a proliferative marker. the aim of this study was to evaluate the immunohistochemical expressions of p53 and pcna in oral leukopla...

Background: Inflammatory myofibroblastic tumor (IMT) is a tumor composed of myofibroblasts and a mixed inflammatory infiltrate that rarely undergoes malignant transformation. The most common sites of involvement include the lung, liver and orbit, but it has been reported to occur in nearly every site of the body, including oral cavity and soft tissue. Although common in other sites, such a tumo...

Lipomas are relatively uncommon benign tumor occurring in the oral cavity with a prevalence rate of 1% to 4% of all oral lesions. They present as a slow growing, painless, asymptomatic submucosal mass and surgical excision is the treatment of choice. Oral lipomas have been known to grow to large sizes causing interference with speech, mastication and construction of denture. A case of 77 years ...

OBJECTIVES The purpose of study was to determine the clinical efficacy of primary tumor volume measurements of different primary sites in the oropharynx compared to the oral cavity. METHODS A retrospective analysis of 85 patients with oral cavity or oropharynx cancer. The tumor area was manually outlined from axial magnetic resonance (MR) series. The software calculated the tumor volumes, aut...