Background:Oral lichen planus (OLP) is considered as a potentially malignant disorder and vascular endothelial growth factor (VEGF) may play a key role in cancer development. The aim of this study was to compare serum and saliva VEGF among patients with OLP, oral squamous cell carcinoma (OSCC) and a healthy control group. Methods:A cross sectional study was pe...

background: detection of cancer at an early stage is of utmost importance to decrease the morbidity and mortality of the disease. apart from the conventional biopsy, non‑invasive methods like analysis of serum and saliva may provide cost‑effective approach for screening a large population. tumor markers are a major part of secondary prevention and thus, the detection of malignancies. the aim of...

background and objectives: squamous cell carcinoma of the tongue (sccot) is the most common malignant neoplasm in oral cavity. at the time of the diagnosis of sccot regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. although the level of healthcare has significantly improved, the survival rate is still low with an un...

Aims: The present study aimed to evaluate the expression of cyclin D1 in oral squamous cell carcinoma and find association with different histological grades carcinoma.
 Study Design: It is a cross sectional study.
 Place Duration Study: Oral samples were collected histopathology laboratory Ziauddin Hospital, North Nazimabad Karachi. Immunohistochemistry was performed multiple discipl...

OBJECTIVES: The purpose of the study was to determine salivary composition Oral squamous cell carcinoma patients. METHODOLOGY: A retrospective conducted over 6 months on data 60 patients obtained from patient records Institute Radiotherapy and Nuclear Medicine, Peshawar. Salivary pH, Sodium, Potassium, total proteins were recorded. RESULTS: protein concentration in saliva oral 23.5 mM/L, 96.7mM...

OBJECTIVE To establish the time trends of the frequency and prevalence of oral cavity cancer in regard to age and gender in a 20-years (time period 1989 - 2008) cohort of Mexicans. DESIGN AND SETTING 13,235 head and neck biopsies from the archive of the Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico were revised. The cases with diagnoses of oral cancer were...

Oral squamous cell carcinoma is the most common malignant epithelial neoplasm affecting the oral cavity. This article overviews the essential points of oral squamous cell carcinoma, highlighting its risk and genomic factors, the potential malignant disorders and the therapeutic approaches. It also emphasizes the importance of the early diagnosis.

The aim of the study is to determine the levels of E-cadherin, vimentin expression in tumor tissues from patients with oral squamous cell carcinoma (OSCC), and the relationship between the expression of E-cadherin, vimentin and epithelial-mesenchymal transition, in order to explore its values for predicting the invasion and metastasis of oral squamous cell carcinoma, short survival of patients ...

Oral squamous cell carcinoma is the sixth most common malignancy worldwide. In Bangladesh, it comprises 20% of the whole body malignancies. Several studies found that 15% to 25% of oropharyngeal cancer cases are associated with human papilloma virus (HPV). This study is done to find the association of human papilloma virus subtypes, particularly HPV type 16 and HPV type 18, with the oral squamo...