OBJECTIVE To determine the prevalence of oral and/or peri-oral piercings in young adults based on a systematic review of the available literature. MATERIAL AND METHODS The MEDLINE-PubMed, Cochrane-CENTRAL and EMBASE databases were comprehensively searched through April 2012 to identify appropriate studies. The prevalence of oral and/or peri-oral piercings was evaluated in the general populati...

background and aims. a correct diagnosis is the most important step in the treatment of oral lesions and each oral lesion has specific clinical features that provide clinical diagnosis; however, some of these features are common among different lesions. in these situations, biopsy and histopathological examination are indicated. the aim of this study was to evaluate the relationship between cli...

the role of oxygen free radicals in the initiation, promotion and progression of carcinogenesis and the protective role of anti-oxidant defenses has been the subject of much speculation in the recent past with conflicting reports in the literature. in recent years, increasing experimental and clinical data have provided compelling evidence for the involvement of oxidative stress in a large numb...

A novel in vitro Caco-2 hepatocyte hybrid system was set up and tested for its ability to predict the oral bioavailability (F) in humans of 24 randomly chosen marketed drugs. Caco-2 cells were cultured on the transwell filters to form tight junctions. Pooled cryopreserved human hepatocytes were placed in the basolateral receiver compartment. To evaluate the permeability and hepatic first pass i...