Optical Coherence Tomography (OCT) has revolutionized ophthalmology. Since its introduction in the early 1990s it has continuously improved in terms of speed, resolution and sensitivity. The technique has also seen a variety of extensions aiming to assess functional aspects of the tissue in addition to morphology. One of these approaches is Doppler OCT (DOCT), which aims to visualize and quanti...

Marie Walde, Benedict Diederich, Bei Cao, Rainer Heintzmann 1 Berlin Institute for Medical Systems Biology, Max Delbrück Center, Robert-Rössle-Str. 10, 13125 Berlin, Germany 2 Institute of Physical Chemistry, Friedrich-Schiller-University Jena, Helmholtzweg 4, 07743 Jena, Germany 3 Xi'an Institute of Optics and Precision Mechanics of CAS, China 4 Leibniz Institute of Photonic Technology, Albert...

This review paper describes the applications of dental optical coherence tomography (OCT) in oral tissue images, caries, periodontal disease and oral cancer. The background of OCT, including basic theory, system setup, light sources, spatial resolution and system limitations, is provided. The comparisons between OCT and other clinical oral diagnostic methods are also discussed.

A review is presented of different scanning, acquisition and processing techniques used to obtain depth-resolved information in optical-coherence tomography (OCT). The principles and performances of different OCT techniques are discussed and images from different types of tissue are presented. Special attention is devoted to the progress in using the time-domain flying spot OCT technique and co...

Purpose To report a case of bilateral choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) visualized utilizing optical coherence tomography angiography (OCT-A). Methods Case report. Results A 29-year-old woman presented with new visual symptoms in both eyes. Fundoscopic exam revealed bilateral multifocal, small, well-defined lesions consistent with PIC. Optical coherenc...

PURPOSE To describe morphological features of the macula in patients with retinopathy of prematurity. METHODS Twelve premature babies with retinopathy of prematurity grades I, II and III underwent dilated fundus examination and optical coherence tomography evaluation. RESULTS In all thirteen eyes of the twelve premature patients optical coherence tomography revealed a condensed retinal pigm...

In adaptive optics, the measurement of spatial coherence length helps in deciding the optimum design parameters of a Shack Hartmann Sensor (SHS). Two methods of estimating the spatial coherence length of optical wavefronts are presented. The first method is based on counting the number of Hough peaks in the wavefront. The second method is based on a simple data mining technique applied on the w...

OCT is based on the principles of low coherence interferometry. Low coherent superluminiscent diode light is directed onto a partially reflective mirror (splitter), whereby two beams are created measurement and reference beams. The measurement beam is directed into the subject’s eye. Here it gets reflected from the boundaries between the microstructures and scattered differently from tissues wi...

Spectroscopic optical coherence tomography (OCT), an extension of conventional OCT, is demonstrated for performing cross-sectional tomographic and spectroscopic imaging. Information on the spectral content of backscattered light is obtained by detection and processing of the interferometric OCT signal. This method allows the spectrum of backscattered light to be measured over the entire availab...

BACKGROUND Retinal vascular diseases are one of the most common causes of blindness in the developed world. Optical Coherence Tomography Angiography (OCT-A) is a new noninvasive method that uses several algorithms to detect blood movement. This enables the creation of high-resolution vascular images with contrast depicting motionless tissue. METHODS This review presents the results of article...