Massive Retinal Gliosis in Neurofibromatosis Type 1 Neurofibromatosis type 1 (NF1), an autosomal dominant syndrome, has major extraocular expressions of bilateral ptosis, diffuse and plexiform neurofibromas, optic nerve gliomas, and dysplasia of the sphenoid bone. With respect to the eyeball, the spectrum of involvement includes enlarged corneal nerves, Lisch iris nodules, dysplasia of the ante...

The data in this article are based on investigations performed in 25 children with suspected septo-optic dysplasia (SOD). There are many signs and methods that help in the diagnosis of SOD. In particular, the ocular fundus, abnormalities of the hypothalamo-pituitary axis and other midline brain structures should be described. In order to achieve a more holistic and functional diagnosis, the deg...

Background: Septo-optic dysplasia (SOD) is a rare condition characterized by midline brain abnormalities, optic nerve hypoplasia and hypothalamic-pituitary deficiencies. Both genetic and environmental factors are involved in its pathogenesis. Genetic abnormalities are identified in only one percent of patients. Objective: To describe varied clinical spectrum of SOD among five children from diff...

tocoagulation was applied and the worm was successfully killed (Figure 1F). The patient reported significant subjective improvement, and his visual acuity measured 20/40 OS 1 month and 20/25 OS 3 months following the initial visit. Spectraldomain OCT showed disruption of the photoreceptors in the papillomacular region secondary to prior photocoagulation but progressive restoration of the normal...

Septo-optic dysplasia (De Morsier syndrome) is a developmental anomaly of mid-line brain structures and includes optic nerve hypoplasia, absence of the septum pellucidum and hypothalamo-pituitary abnormalities. We describe seven patients (four female, three male) who had at least two out of the three features necessary for the diagnosis of septo-optic dysplasia. Four patients had hypopituitaris...

This article reviews the case of a 29-year-old woman who underwent revision rhinoplasties. Preoperative photographs and postoperative photographs 1 year after surgery are included.