BACKGROUND Adjuvant radiation therapy (RT) with temozolomide (TMZ) is standard of care for high grade gliomas (HGG) patients. RT is commonly started 3 to 5 weeks after surgery. The deformation of the tumor bed and brain from surgery to RT is poorly studied. This study examined the magnitude of volume change in the postoperative tumor bed and the potential impact of RT planning. METHOD AND MAT...

The present case report was a 36-year female with lesion on the right side of inner lower lip and diagnosed as pyogenic granuloma occurring at an unusual site. presently available treatment for is surgical excision which might delay wound healing due to complications such intraoperative bleeding post operative infection. Other modalities cryosurgery, CO2 Nd:YAG lasers, flash lamp pulsed dye abl...

Between 1964 and 1991, vaginal hysterectomy was performed in 60 patients with clinical stage I endometrial carcinoma, who were not considered candidates for the conventional surgical approach. Of these patients, 66.7% were obese with a median weight of 235 pounds. Other risk factors included hypertension (63%), diabetes mellitus (34%), cardiac disease (28%) and pulmonary disease (12%). Operativ...

OBJECTIVE To characterize complications of prostate cancer therapy and operative management in patients referred to our institution for surgical intervention. MATERIALS AND METHODS Data was abstracted from a retrospectively collected single surgeon database at a large tertiary care referral-based medical center. Variables included age, prostate cancer therapy, complication(s) and their manage...

OBJECTIVE Auricular defects are challenging to reconstruct with native tissue. We describe operative techniques and complication management for patients undergoing osseointegrated implants for auriculectomy defects and microtia. SETTING Tertiary referral center. PATIENTS All patients at Duke University Medical Center with auricular defects treated with osseointegrated implants for prostheti...

OBJECTIVE To establish the pre-operative simultaneous integrated boost intensity-modulated radiation therapy (SIB-IMRT) technology in preparing the surgical boundary of extremity soft tissue sarcoma (ESTS), aiming to investigate its impacts towards the short-term local control and post-operative wound complications of ESTS. PATIENTS AND METHODS 16 patients with local advanced ESTS were prospe...

Primary tracheal tumors are rare neoplasms which often present with indolent and nonspecific symptoms. Despite a tendency for late presentation, more than half of patients with benign and malignant neoplasms will be candidates for curative resection upon diagnosis. This review describes the diagnostic and staging evaluation of tracheal neoplasms. Curative surgical procedures including laryngotr...

Purpose: A systematic review was conducted to develop guidelines for radiotherapy in adult patients with newly diagnosed malignant glioma. Methods: MEDLINE, CANCERLIT, the Cochrane Library, and relevant conference proceedings were searched to identify randomized trials and meta-analyses. Results: Pooling of six randomized trials detected a significant survival benefit favouring post-operative r...