to that of the 12 patients who had pretransplant splenectomy (91.6 ± 7.9% and 66.1 ± 13.8% respectively). Posttransplant splenectomy produced the desired effects in all 11 patients in that the leukopenia was permanently reversed, significantly higher doses of cytotoxic drugs were tolerated, and serum creatinine levels declined. Although the numbers are small, this preliminary study is encouragi...

BACKGROUND Splenectomy is associated with increased risk for bacteremia, due to impaired clearance of bloodborne agents and to altered phagocytosis and humoral immunity. We conducted a retrospective cohort study of patients at risk for splenectomy for a 13-year period to determine immunization coverage, and outcomes of those with and without splenectomy, and with or without receipt of influenza...

OBJECTIVE To determine the surgical outcome of splenectomy in children with thalassemia major. METHODS It is an observational and descriptive study conducted in Department of Paediatric Surgery in collaboration with hematology, radiology, anesthesia and paediatric intensive care department at The Children's Hospital and the Institute of Child Health, Multan during the period of September 2007...

Little epidemiological research is available on the relationship between splenectomy and renal and perinephric abscesses. The purpose of the study was to examine this issue in Taiwan.We conducted a population-based retrospective cohort study using the hospitalization dataset of the Taiwan National Health Insurance Program. A total of 16,426 participants aged 20 and older who were newly diagnose...

The aim of the study. Retrospective analysis of indications for splenectomy in hematological diseases, positive effect of this operation and correlations between objective prognostic factors and good response to splenectomy in patients with different hematological indications for splenectomy. Material and methods. 98 adult patients with hematological disorders, who were splenectomised in the ye...

INTRODUCTION Laparoscopic splenectomy has become the procedure of choice for those patients who need to have a splenectomy. The skills required to perform a laparoscopic splenectomy are not easy to learn and therefore may limit the availability of this procedure to patients. METHODS We present a hand-assisted technique that allows the performance of a laparoscopic splenectomy safely and rapid...

The spleen is a crucial organ in humans. Little is known about the association between stroke and splenic injury or splenectomy. The aim of this study was to determine the risk of stroke in patients with splenic injury and splenectomy.A nationwide cohort study was conducted by analyzing the National Health Insurance Research Database in Taiwan. For comparison, control patients were selected and...

BACKGROUND The influence on the antitumor immune system after splenectomy in vivo are controversial. CD4+CD25+Foxp3+T-cells (regulatory T-cell: reg T) and natural killer (NK) cells play important roles in immunological tolerance and antitumor immunity. The influence of splenectomy on the antitumor immune system was evaluated in a metastasis induced mouse model. MATERIALS AND METHODS Experimen...

laparoscopic trocar site interparietal hernia is a rare type of incisional hernia, which has been rarely reported. this type of hernia is usually observed when the fascia or peritoneum is not repaired or not completely closed. this complication may lead to some serious problems. we aimed to report a case of port site interparietal hernia after laparoscopic splenectomy.

splenic tuberculosis is a rare entity, particularly among immunocompetent hosts. hererin, we present a 23 year-old man who was reffered with fever of unknown origin and eventually diagnosed to have splenic tuberculosis with an involvement of a single axillary lymph node as the sole site disease in the other organs.despite two months of treatment with antituberculous agents due to necrotising gr...