Recently, it has been more and more popular to build hybrid storage systems on the basis of SSD (Solid State Drives) and HDD (Hard Disk Drive). In order to evaluate the performance of various hybrid storage based algorithms, this paper proposes a flexible simulation tool called SH-Sim. SH-Sim aims to provide a flexible virtual hybrid disk which is made up of a virtual SSD and a virtual HDD. SH-...

Kaposi's sarcoma-associated herpesvirus (KSHV) stabilizes hypoxia-inducible factor α (HIF-1α) during latent infection, and HIF-1α reactivates lytic replication under hypoxic stress. However, the mechanism utilized by KSHV to block lytic reactivation with the accumulation of HIF-1α in latency remains unclear. Here, we report that LANA encoded by KSHV contains a unique SUMO-interacting motif (LAN...

In this paper, some results of Singh, Gopalakrishna and Kulkarni (1970s) have been extended to higher order derivatives. It has been shown that, if $sumlimits_{a}Theta(a, f)=2$ holds for a meromorphic function $f(z)$ of finite order, then for any positive integer $k,$ $T(r, f)sim T(r, f^{(k)}), rrightarrowinfty$ if $Theta(infty, f)=1$ and $T(r, f)sim (k+1)T(r, f^{(k)}), rrightarrowinfty$ if $Th...

While dealing with vague concepts often it puts us in fix to determine whether to a particular situation/case/state a particular concept applies or not. A human perceiver can determine some cases as the positive instances of the concept, and some as the negative instances of the same; but there always remain cases, which might have some similarities with some positive cases, and also have some ...

This question assumes that we would want to control a SIM, rather than granting it complete freedom. Science fiction abounds with stories in which a SIM pursues a plan that does not please its human creators. For example, Colossus (the inspiration for the movie The Forbin Project) presents a plausible scenario involving a SIM created to manage the nuclear weaponry of the USA [6]. In the end, th...