The relationship between the configuration of the mating type locus (MTL) and white-opaque switching in Candida albicans has been examined. Seven genetically unrelated clinical isolates selected for their capacity to undergo the white-opaque transition all proved to be homozygous at the MTL locus, either MTLa or MTLalpha. In an analysis of the allelism of 220 clinical isolates representing the ...

tIHE Council begs to present the seventy-second anntual report of the Society. Tlhe roll of the Society now stands as follows T'his 1Year Last Year Honorary Fellows 7 9 Life Fellows 13 11 Life MNem-nbers (under o0l regtulationis) 2 2 Fellowxs 274 243 Members 39 During the sessioni the Societv has lost by (leath Sir WN'illiam \Vhitla, M.A., MI.D., LL.D., Honorary Fellow, Presi(lent 1886-7, 1901-...

Abstract. Sea ice albedo plays an important role in modulating the climate of Earth and is affected by low background concentrations oil droplets within matrix that absorb solar radiation. In this study, response three different types bare sea (melting, first-year, multi-year ice) are calculated at increasing mass ratios (0–1000 ng g?1) crude using a coupled atmosphere–sea radiative-transfer mo...

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Opaque selling is a mechanism whereby a seller conceals product or price information from buyers prior to purchase. Over time opaque intermediaries, such as Hotwire and Priceline.com, have emerged as an established distribution channel for the travel industry. The opaque channel has two countervailing effects: it can increase sales by attracting price-sensitive travelers who may otherwise not p...

Rendering refractive caustics from transparent objects on opaque objects is computationally intensive. This paper presents a fast rendering technique for transparent objects and refractive caustics due to transparent objects on the opaque object. To calculate the intensities of caustics, we set virtual planes around the opaque object and store the intensities of caustics on the virtual planes a...

The repair of a fractured porcelain surface with a resin composite was investigated. The effects of applying an opaque resin to porcelain surfaces, which were silanated by a ceramic primer from a repair kit or by an experimental silane coupling agent, were studied. The porcelain surfaces were silanated for 10 sec and 60 min. Three types of adherents were evaluated: opaque resin with light irrad...

Many systems run rich analytics on sensitive data in the cloud, but are prone to data breaches. Hardware enclaves promise data confidentiality and secure execution of arbitrary computation, yet still suffer from access pattern leakage. We propose Opaque, a distributed data analytics platform supporting a wide range of queries while providing strong security guarantees. Opaque introduces new dis...

Non-genetic phenotypic variations play a critical role in the adaption to environmental changes in microbial organisms. Candida albicans, a major human fungal pathogen, can switch between several morphological phenotypes. This ability is critical for its commensal lifestyle and for its ability to cause infections. Here, we report the discovery of a novel morphological form in C. albicans, refer...

Candida albicans WO-1 switches reversibly and at high frequency between a white and an opaque colony-forming phenotype that includes dramatic changes in cell morphology and physiology. A misexpression strategy has been used to investigate the role of the opaque-phase-specific gene PEP1 (SAP1), which encodes a secreted aspartyl proteinase, in the expression of the unique opaque-phase phenotype a...