We report a family with 15 individuals affected with multiple sclerosis present in three and possibly four generations. The segregation of multiple sclerosis within this pedigree is consistent with an autosomal dominant mode of inheritance with reduced penetrance. The clinical characteristics of the affected individuals are indistinguishable from those seen in sporadic multiple sclerosis with r...

Objectives. In the present study, we aimed to compare the childhood and adult onset multiple sclerosis patients prospectively in their adulthood on the basis of clinical and magnetic resonance imaging (MRI) findings and cognitive impairment, which have not been performed before. Patients and Methods. Forty-six patients in whom the disease onset occurred before 16 years of age were included in t...

Multiple sclerosis can follow very different patterns of evolution and variable rates of disability accumulation. This raises the issue whether it represents one or several distinct diseases. We assessed demographic and clinical characteristics in 1844 patients with multiple sclerosis that we categorized according to the classification of Lublin and Reingold (1996) into 1066 (58%) relapsing-rem...

from september 18th - 20th, 2015, the 1st international razavi multiple sclerosis congress was held in mashhad, iran. the meeting was designated as a platform especially for young scientists to get internationally connected, discuss recent scientific findings and develop further ideas for strategic collaborations between germany and iran. physicians and scientists from research groups working i...

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dream should be considered as a kind of cognitive ability that is formed parallel to other cognitive capabilities like language. on the other hand, multiple sclerosis (ms) is a complex disease that can involve different aspects of our cognition. therefore, ms may influence patients' dreams. in fact, we do not know what the importance of dream is in ms, but further studies may introduce dream an...

abstract introduction: psychodrama, as a form of art therapy, helps people to enact and use role-plays for a specific problem, rather than just talking about it, in an effort to review the problem, gain feedback from group members, find appropriate solutions, and practice them for their life. the current paper aims to investigate the effectiveness of psychodrama therapy on the reduction of depr...

background: multiple sclerosis (ms) is an inflammatory and demyelinating disease of central nervous system (cns). the aim of the present study was to determine the type and the frequency of initial presenting symptoms in patients with ms and their relation with demographic characteristics in babol, northern iran. methods: all patients of this study were recruited over a ten year period from 200...

multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. the imbalance between the t cell effectors and t cell regulators is thought to have a role in the pathogenesis of the disease. melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. melatonin ...