نتایج جستجو برای: ono equation

تعداد نتایج: 231315  

2017
Eydie Miller Ellis Michael S Berlin Caroline L Ward John A Sharpe Alam Jamil Alon Harris

BACKGROUND/AIMS ONO-9054 is being developed for the reduction of intraocular pressure (IOP) in patients with ocular hypertension (OHT) and open-angle glaucoma (OAG). This study compared the novel dual EP3/FP agonist ONO-9054 with the FP agonist Xalatan. METHODS Adults (n=123) with bilateral mild/moderate OAG or OHT, with unmedicated IOP of ≥24 mm Hg at 8:00 hours, ≥21 mm Hg at 10:00 hours and...

Journal: :Carcinogenesis 2007
Hiroki Makita Michihiro Mutoh Takayuki Maruyama Kazuhiro Yonemoto Atsushi Kobayashi Hideki Fujitsuka Makoto Toida Toshiyuki Shibata Shingo Miyamoto Yumiko Yasui Rikako Suzuki Keiji Wakabayashi Takuji Tanaka

We previously reported that certain cyclooxygenase (COX) inhibitors could inhibit chemically induced tongue carcinogenesis. In the present study, we investigated the effects of prostaglandin E(2) (PGE(2)) receptor EP(1)-selective antagonist ONO-8711 on 4-nitroquinoline 1-oxide (4-NQO)-induced oral carcinogenesis to know whether an EP(1) receptor involves in oral carcinogenesis. Male Fischer 344...

Journal: :Journal of Differential Equations 2021

For initial data in Sobolev spaces H s ( T ) , 1 2 < ? the solution to Cauchy problem for Benjamin-Ono equation on circle is shown grow at most polynomially time a rate + t 3 ? ? 0 ? . The key establishing this result discovery of nonlinear smoothing effect equation, according which satisfied by certain gauge transform, widely used well-posedness theory problem, becomes smoother once its free r...

2005
Nikola Popović Tasso J. Kaper

We investigate traveling wave solutions in a family of reaction-diffusion equations which includes the Fisher–Kolmogorov–Petrowskii–Piscounov (FKPP) equation with quadratic nonlinearity and a bistable equation with degenerate cubic nonlinearity. It is known that, for each equation in this family, there is a critical wave speed which separates waves of exponential decay from those of algebraic d...

2008
Didier Pilod

We study the higher-order nonlinear dispersive equation ∂tu+ ∂ 2j+1 x u = ∑ 0≤j1+j2≤2j aj1,j2∂ j1 x u∂ j2 x u, x, t ∈ R. where u is a real(or complex-) valued function. We show that the associated initial value problem is well posed in weighted Besov and Sobolev spaces for small initial data. We also prove ill-posedness results when a0,k 6= 0 for some k > j, in the sense that this equation cann...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2012
Qing Xu Mizuho Nakayama Yoshinori Suzuki Katsuya Sakai Takahiro Nakamura Yoshiki Sakai Kunio Matsumoto

Previous studies have demonstrated that mice disrupted with the cyclooxygenase-2 gene showed much more severe liver damage compared with wild-type mice after liver injury, and prostaglandins (PGs) such as PGE(1/2) and PGI(2) have decreased hepatic injury, but the mechanisms by which prostaglandins exhibit protective action on the liver have yet to be addressed. In the present study, we investig...

Journal: :Annales de l'Institut Henri Poincaré C, Analyse non linéaire 2013

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