ith great interest we read the article by Li et al. (1) regarding asomotor functional responses of a conduit coronary artery distal o sirolimus-eluting stents in a porcine model. The researchers tated in the discussion, “. . .most of the drug taken up into cardiac issue was transferred by direct contact with the arterial wall, which ay have served as a reservoir for subsequent transfer via diff...

How is it diagnosed? Your doctor will ask about the pain, listen to your heart, and check for signs of fluid around your heart. He or she may order a test called an electrocardiogram, which shows the electrical activity of your heart. You may need more tests, such as a chest x-ray, an ultrasound of your heart, and blood tests. How is it treated? It is treated with nonsteroidal anti-inflammatory...

The first of a new class of pharmaceutical therapies for hepatitis C with cure rates in clinical trials of over 90% were released into the Canadian marketplace in late 2014, but treatment has come with a high price tag for both private and public payers [1]. In this article we examine the prevalence of hepatitis C, the cost of new treatment options and the implications of coverage under public ...

In August 1997, Congress enacted the State Children’s Health Insurance Program (SCHIP), with bipartisan support, as Title XXI of the Social Security Act. SCHIP gives states a higher federal match than Medicaid—that is, a higher federal contribution for every dollar of state funds spent on the program. In contrast to Medicaid, however, SCHIP’s federal contribution is not an open-ended entitlemen...

As CPU cores become both faster and more numerous, the limiting factor for most programs is now, and will be for some time, memory access. Hardware designers have come up with ever more sophisticated memory handling and acceleration techniques–such as CPU caches–but these cannot work optimally without some help from the programmer. Unfortunately, neither the structure nor the cost of using the ...