Post-COVID syndrome was described in the context of a survey prolonged COVID-19 symptoms for first time 2020, run by Patient-Led Research Collaborative, citizen’s scientist group. Symptoms persisting more than three weeks after diagnosis fall into category post-COVID syndrome. The most common include fatigue, dyspnea, olfactory and gustatory dysfunction, chest pain, myalgia, sleep mental disord...

Intranasal medications are used to treat various nasal disorders. However, their effects on olfaction remain unknown. Zicam (zinc gluconate; Matrixx Initiatives, Inc), a homeopathic substance marketed to alleviate cold symptoms, has been implicated in olfactory dysfunction. Here, we investigated Zicam and several common intranasal agents for their effects on olfactory function. Zicam was the on...

Both observations in humans with disorders of dopaminergic transmission and molecular studies point to an important role for dopamine in olfaction. In this study we found that dopamine receptor activation in the olfactory bulb causes a significant depression of synaptic transmission at the first relay between olfactory receptor neurons and mitral cells. This depression was found to be caused by...

The expression of ectopic olfactory receptors (ORs) in melanized cells, such as the human brain nigrostriatal dopaminergic neurons and skin melanocytes, is here pointed out. ORs are recognized to regulate skin melanogenesis, whereas OR expression in the dopaminergic neurons, characterized by accumulation of pigment neuromelanin, is downregulated in Parkinson's disease. Furthermore, the correlat...

it is not known whether the instincts of wild horses have remained strong during their centuries of domestication. knowledge of this matter would give riders the opportunity to know more about the behavior of horses and consequently about safety for both horses and riders. in this current research, we studied the behavior of fifteen caspian miniature horses of different ages and sexes using sti...

Abstract The ongoing pandemic of Coronavirus disease 2019 (COVID-19) has infected more than 27 million confirmed cases and 8,90,000 deaths all around the world. Verity viral infections can infect nervous system; these present a wide range manifestation. aim current study was to systematically review COVID-19 associated central system manifestations, mental neurological symptoms. For that we con...

Major depressive disorder (MDD) occurs with a high prevalence among mental illnesses. MDD patients experience sadness and hopelessness, with blunted affective reactivity. However, such depressive episodes are also key symptoms in other depressive disorders, like Bipolar Disorder (BPD) or Seasonal Affective Disorder (SAD). Moreover, depressive symptoms can also be found in healthy individuals, b...