نتایج جستجو برای: oil adjuvant vaccine
تعداد نتایج: 285981 فیلتر نتایج به سال:
Recombinant subunit vaccines are an efficient strategy to meet the demands of a possible influenza pandemic, because of rapid and scalable production. However, vaccines made from recombinant hemagglutinin (HA) subunit protein are often of low potency, requiring high dose or boosting to generate a sustained immune response. We have improved the immunogenicity of a plant-made HA vaccine by chemic...
Blackleg in cattle has been recognized since 1938 in Iran that mostly affects cattle in enzootic farm. Main object of this study was to prepare and formulate a concentrated potent vaccine for immunization of cattle against blackleg in Iran. Experimental concentrated blackleg vaccine was prepared according to the method described by FAO. The medium (Modified medium for production of experiment...
Objective(s): Many types of human papillomaviruses (HPVs) have been identified, with some leading to cancer and others to skin lesions such as anogenital warts. Studies have demonstrated an association between oncogenic HPV and cervical cancer and many researchers have focused on therapeutic vaccines development. At present, the modulatory effect of opioids on the innate and acquired immune sys...
Lymph node–targeting adjuvant AMP-CpG enhances SARS-CoV-2 RBD vaccine-induced cellular and humoral immune responses.
In a region of high endemicity of trachoma and typhoid in Eastern Saudi Arabia, a vaccination program was undertaken to determine whether the administration of chemically inactivated trachoma viruses to children under 3 years of age would reduce the incidence of trachoma among the vaccinees. For several reasons, the decision was reached that trachoma vaccines should be contrasted with typhoid v...
BACKGROUND Vaccination against seasonal influenza strains is recommended for "high risk" patient groups such as infants, elderly and those with respiratory or circulatory diseases. However, efficacy of the trivalent influenza vaccine (TIV) is poor in many cases and in the event of an influenza pandemic, mono-valent vaccines have been rapidly developed and deployed. One of the main issues with u...
Due to a large number of mutations in the spike protein and immune escape, Omicron variant (B.1.1.529) has become predominant concern (VOC) strain. To prevent disease, we developed candidate inactivated vaccine (Omicron COVID-19 Vaccine (Vero Cell), Inactivated). evaluate safety vaccine, tested repeat-dose toxicity Sprague-Dawley (SD) rats. The doses were administered randomly three groups: phy...
The present study was conducted to assess the effects of propolis flavonoid used as adjuvant on the immune response of Landrace-Yorkshire hybrid sows immunized with an inactivated vaccine of porcine parvovirus (PPV). Thirty Landrace-Yorkshire hybrid sows were randomly assigned to one of 3 groups, and the sows in two adjuvant groups were intramuscular injected PPV vaccine with 2.0 mL propolis fl...
BACKGROUND There is an urgent need for a vaccine that is effective against the 2009 pandemic influenza A (H1N1) virus. METHODS A split-virus, inactivated candidate vaccine against the 2009 H1N1 virus was manufactured, and we evaluated its safety and immunogenicity in a randomized clinical trial. Subjects were between 3 and 77 years of age, stratified into four age groups. The immunization sch...
Mucin 1 (MUC1) is a tumor-associated antigen that is overexpressed in several adenocarcinomas. However, clinical trials with MUC1 showed that MUC1 is a relatively poor immunogen in humans. In view of the low immunogenicity of this protein vaccine, we designed a method based on an immunoadjuvant and immunization strategy to enhance the cellular immune response to this protein vaccine. DDA/MPL ha...
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