There is concern that intracytoplasmic sperm injection (ICSI) may lead to offspring with a high frequency of chromosomal abnormalities. Accordingly, we studied spermatozoa sampled from eight infertile men with oligoasthenoteratozoospermia (OAT) by multi-colour fluorescence in-situ hybridization (FISH), using DNA probes for chromosomes 13, 18, 21, X and Y. Results were compared with those of spe...

The practice of gamete donation has, until recently, been shrouded in secrecy. The stigma associated with infertility and, in particular, donor insemination has been the main factor contributing to this secrecy. Over the last 20 years, this secrecy and the anonymity of the gamete donors has been challenged. In the first instance, the challenge came from governments in some countries legislating...

background: This paper presents finding from a study of the emotional and relational aspects of egg-sharing, exploring egg-share donors’ and recipients’ thoughts and feelings about each other, about each other’s treatment outcome and any resulting children, as well as their attitudes towards disclosure of donor origins and contact between donors and donor offspring in the future. It is the firs...

introduction: combination of congenital diaphragmatic hernia (cdh) and anorectal malformation (arm) is rare. in this report, we describe a combination of imperforate anus and cdh in one of twins who conceived by assisted reproductive technology (art). case report: a female preterm newborn at 27 weeks of gestation was referred to our neonatal intensive care unit due to respiratory distress. she ...

This research was designed to study sexual differences in place conditioning induced by morphine in offspring born of female Wistar rats mated with drug-naïve males. Mothers were exposed to morphine during the 14th-16th days of gestational. Control dams were simply saline-injected. Female and male virgin offspring born of morphine-treated or saline-treated mothers were separately housed until b...

Background: Comparison of obstetric and neonatal outcomes of twin pregnancies conceived by assisted reproduction technology (ART) with those of spontaneously conceived (SC). Materials and Methods: In this prospective cohort study, all dichorionic twin pregnancies following fresh IVF/ intra-cytoplasmic sperm injection (ICSI) or ICSI cycles (n=320) and (SC) (n=170) in nulliparous women in Royan I...

We utilized a vitamin D receptor (VDR) gene knockout model to study the effects of maternal and fetal absence of VDR on maternal fertility, fetal-placental calcium transfer, and fetal mineral homoeostasis. Vdr null mice were profoundly hypocalcemic, conceived infrequently, and had significantly fewer viable fetuses in utero that were also of lower body weight. Supplementation of a calcium-enric...

Behavioral and demographic factors such as group size, social structure, dispersal patterns, and mating systems affect male reproductive success. In the present study, we analyze the relationship between social structure, genetic relatedness of adult males and offspring paternity in one population of Alouatta caraya inhabiting a continuous forest in Northern Argentina. After 14 months of behavi...

The social and legal acceptability of third-party reproduction varies around the world. In Australia, gamete and embryo donation and surrogacy are permitted within the regulatory framework set out by federal and state governments. The aim of this paper is to describe the social context and regulatory framework for third-party reproduction in Australia. This is a review of current laws and regul...