Cranial radiation therapy (CRT) is an effective treatment for pediatric central nervous system malignancies, but survivors often suffer from neurological and neurocognitive side effects that occur many years after radiation exposure. Although the biological mechanisms underlying these deleterious side effects are incompletely understood, radiation exposure triggers an acute inflammatory respons...

Describing and explaining learning in complex settings makes high demands on educational research strategies. This paper roughly outlines a pattern-oriented research strategy, aiming to bridge the gap between theory and practice and facilitating improvements in complex social settings like collaborative learning. The ideas underlying this approach are rooted in theorybased evaluation, Realistic...

This study contributes to research on changing gender ideologies in marriage by focusing on a unique group of marriage innovators. We compare and contrast newlywed couples who chose covenant marriage, a new legal option in Louisiana primarily attractive to those of evangelical faiths, with couples who chose standard marriage. With quantitative and qualitative data from the Marriage Matters proj...

The literature on the indispensability argument for mathematical realism often refers to mathematics’ ‘indispensable explanatory role.’ I argue that we should examine the notion of explanatory indispensability from the point of view of specific conceptions of scientific explanation. The reason is that explanatory indispensability in and of itself turns out to be insufficient for justifying the ...

Hepatitis B virus (HBV) suppresses innate immune signaling to establish persistent infection. Although HBV is a DNA virus, its pre-genomic RNA (pgRNA) can be sensed by RIG-I and activates MAVS to mediate interferon (IFN) λ synthesis. Despite of the activation of RIG-I-MAVS axis by pgRNA, the underlying mechanism explaining how HBV infection fails to induce interferon-αβ (IFN) synthesis remained...

This paper investigates the determinants of tourism inflows to Greece. The significance of the specific sector for the Greek economy varies from 15% to 20% of GDP (measured directly or indirectly respectively). Building on the existing literature, panel data estimation techniques are used, with explanatory variables including selected macroeconomic indicators and (relative) price indices. The m...