AbstrAct: Cycle-correlated variation in olfactory threshold, with women becoming more sensitive to odors mid-cycle, is somewhat supported by the literature but the evidence is not entirely consistent, with several studies finding no, or mixed, effects. It has been argued that cyclic shifts in olfactory threshold might be limited to odors relevant to the mating context. We aimed to test whether ...

Humans use a repertoire of > 400 olfactory receptors (ORs) to perceive odorants. The sense smell is complex trait whereby genetics and environmental factors interplay. To date, still little known regarding the smell, even though high genetic variability ORs genes has already been demonstrated. Recently significant association between cinnamon odorant recognition rs317787 polymorphism, located i...

Odorous emissions from wastewater treatment plants (WWTPs) cause negative impacts on the surrounding areas and possible health risks nearby residents. However, efficient reliable identification of WWTPs’ odorants is still challenging. In this study, odorous volatile organic compounds (VOCs) domestic at different processing units were profiled identified using gas chromatography-ion mobility spe...

What are odorants? ‘Odorants’ are individual chemical compounds, entities in the atmosphere which are capable of being transposed by our nervous systems into what we term ‘odours’. ‘Odours’ are the subjective products of neural stimulation in the brain and therefore have the potential to be modulated by individual influences. The memory and emotional areas of the brain are often stimulated duri...

Odorants are detected by a large family of odorant receptors (ORs) expressed in the nose. The information provided by the ORs is transmitted to specific regions of the brain, leading to odorant perception. The determination of the odorant specificities of the different ORs will contribute to the understanding of how odorants are discriminated by the olfactory system. However, to date only a few...

This paper proposes a neural network model for prediction of olfactory glomerular activity aimed at future application to the evaluation of odor qualities. The model's input is the structure of an odorant molecule expressed as a labeled graph, and it employs the graph kernel method to quantify structural similarities between odorants and the function of olfactory receptor neurons. An artificial...

The fruit fly, Drosophila melanogaster, is equipped with a sophisticated olfactory sensory system that permits it to recognize and discriminate hundreds of discrete odorants. The perception of these odorants is essential for the animal to identify relevant food sources and suitable sites for egg-laying. Advances in the last year have begun to define the molecular basis of this insect's discrimi...

Odorants are volatile molecules that efficiently carry chemical information, providing one of the main ways for communicating with the environment in all kingdoms of life. In the other hand, mammalian genomes codify for hundreds of olfactory receptors (ORs), e.g. about 400 in human and more than 1000 in mouse, underlying the crucial role of the sense of smell during evolution. Therefore, the ol...