The sorption of VOCs by different building materials can significantly affect VOC concentrations in indoor environments. In this paper, a new model has been developed for simulating VOC sorption and desorption rates of homogeneous building materials with constant diffusion coefficients and material-air partition coefficients. The model analytically solves the VOC sorption rate at the material-a...

BACKGROUND: The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for this analysis. PKQuest is a new generic PBPK that is designed to avoid this problem by using a set of "standard human" default parameters that are applicable to most solutes. RESULTS: PKQuest is used to model the ...

In order to measure the similarity between two partitions coming from the same data set, we study extensions of the RV-coefficient, the kappa coefficient proposed by Cohen (in case of partitions with same number of classes), and the D2 coefficient proposed by Popping. We find that the RV coefficient is identical to the Janson and Vegelius index. We compare the result coming from kappa’s coeffic...

The odorant partition coefficient is a physicochemical property that has been shown to dramatically influence odorant deposition patterns in the mammalian nose, leading to a chromatographic separation of odorants along the sensory epithelium. It is unknown whether a similar phenomenon occurs in fish. Here we utilize molecular dynamics simulations, based on a simplified molecular model of olfact...

We describe a method, called affinity partitioning, for the purification of proteins containing specific ligand binding receptor sites. This method adds specificity to the procedures for protein purification with aqueous polymer two-phase systems by introduction of a polymer derivative, coupled to an appropriate ligand. The addition of a polymer-ligand that partitions predominantly into one pha...

Background: The 153Sm-[tris(1,10-phenanthroline) Samarium(III)]complex (153Sm-PL3) was prepared in view of development of targeting therapeutic compounds for malignancies, and interesting in-vitro anti-tumor activities of lanthanide phenanthroline complexes,. Materials and Methods: Sm-153 chloride was obtained by thermal neutron flux (4 × 1013 n.cm-2.s-1) of enriched 152Sm2O3 sample, diss...