Mycotoxins present in fodders may evoke health problems of animals and people. The data published by FAO in 2001 show that 25% of raw materials are contaminated with mycotoxins, while their type and concentration are to a great extent dependable on the climatic zone. Biological detoxification of mycotoxins by the use of microorganisms is one of the well-known strategies for the management of my...

In this paper, we developed a simple method to detect fungi toxin (ochratoxin A) produced by Aspergillus Ochraceus and Penicillium verrucosumm, utilizing graphene oxide as quencher which can quench the fluorescence of FAM (carboxyfluorescein) attached to toxin-specific aptamer. By optimizing the experimental conditions, we obtained the detection limit of our sensing platform based on bare graph...

Ochratoxin A (OTA)-a toxin produced by Aspergillus carbonarius, Aspergillus ochraceus, and Penicillium verrucosum-is one of the most-abundant food-contaminating mycotoxins. To avoid the risk of OTA consumption for humans and animals, the rapid detection and quantitation of OTA level in different commodities are of great importance. In this work, an impedimetric immunosensor for ochratoxin A (OT...

G. A. SANSING, E. B. LrLLEHOJ, R. W. DHROY and M. A. MILLER. Synergistic toxic effects of citrinin, ochratoxin A and penicillic acid in mice. Toxicoll 14, 213-220, 1976.-The LD50'S in mice of citrinin, ochratoxin A, and penicillic acid injected intraperitone,"lIy were 89,22, and 100 mg per kg of body weight, respectively. Paired combinations of the mycotoxins, citrinin: ochratoxin A (Cl:OA), oc...

Mycotoxins are toxic secondary fungal metabolites. A large variety of mycotoxins have been described, but only a minority of them occur regularly in feed and food items under normal conditions and pose a risk to feed and food safety. The important moulds producing toxins during storage belong to the genera of Penicillium, or Aspergillus. The most important storage toxins are probably ochratoxin...

The extraction of ochratoxin A from meat products is generally carried out using chlorinated organic solvents, such as chloroform or methyl chloride, acidified with hydrochloric or o-phosphoric acid. In this study, an innovative method was developed to extract ochratoxin A from pork and dry-cured ham samples. The method was based on an enzyme-assisted extraction with pancreatin in phosphate buf...

Allosteric communication in proteins is a fundamental and yet unresolved problem of structural biochemistry. Previous findings, from computational biology ( Ota, N.; Agard, D. A. J. Mol. Biol. 2005 , 351 , 345 - 354 ), have proposed that heat diffuses in a protein through cognate protein allosteric pathways. This work studied heat diffusion in the well-known PDZ-2 protein, and confirmed that th...

Mould and mycotoxin contamination in food OTA toxicity Ochratoxin A producers Occurrence of Ochratoxin A Effect of water activity on OTA production OTA destruction during roasting of coffee Levels and distribution of OTA in green coffee (contamination, survey) Effect of processing and handling on OTA content of green coffee Effect of caffeine on OTA production Socioeconomic impact of coffee pro...