UNLABELLED Our goal was to determine whether scintigraphy with 111In-DTPA-paclitaxel could predict the response to chemotherapy with paclitaxel. METHODS Ovarian carcinoma (OCA 1), mammary carcinoma (MCA-4), fibrosarcoma (FSA) and squamous cell carcinoma (SCC VII) were inoculated into the thighs of female C3Hf/Kam mice. Mice bearing 8 mm tumors were treated with paclitaxel (40 mg/kg). The grow...

The physical, chemical, and functional properties of starches isolated from the Andean tubers oca (Oxalis tuberosa M.), olluco (Ullucus tuberosus C.) and mashua (Tropaeolum tuberosum R. & P.) were studied. The tubers were obtained from a local grocery. The morphology of the starch granules (size and shape) was studied with scanning electron microscopy (SEM), which revealed ellipsoid, oval, coni...

The aim of this study was to investigate the occlusal contact area (OCA) in individual teeth during low-level tooth clenching in 24 healthy participants. Before measurements were made, the 100% maximum voluntary contraction (MVC) was determined. At baseline, all subjects were instructed to close their mouth and touch the opposing teeth with minimal force. Occlusal contact was recorded during th...

Purpose To present the Organizational Courage Assessment (OCA) and explore its construct validity. Design/Methodology/Approach The OCA assesses the frequency that members (1) observe potential acts of courage in their organization and (2) fear performing those acts of courage—which defines four types of organizations: bureaucratic organizations (little fear with few acts of courage), fearful or...

Oculocutaneous albinism (OCA) is a group of inherited disorders characterized by defective melanin biosynthesis. OCA1, the most common and severe form, is caused by mutations in the tyrosinase (TYR) gene. OCA4, caused by mutations in the SLC45A2 gene, has frequently been reported in the Japanese population. To determine the mutational spectrum in Korean OCA patients, 12 patients were recruited....

B and T lymphocytes arise from a common precursor in the bone marrow, but ultimately acquire very different functions. The difference in function is largely attributable to the expression of tissue-specific transcription factors that activate discrete sets of genes. In previous studies we and others have shown that the specialized genes expressed by Ig-secreting cells cease transcription when t...

Pigmentation disorders span the genetic spectrum from single-gene autosomal recessive disorders such as oculocutaneous albinism (OCA), the autosomal dominant disorder piebaldism to X-linked ocular albinism and multifactorial vitiligo. OCA connotes a group of disorders that result in hypopigmented skin due to decreased melanin production in melanocytes and loss of visual acuity. There are four n...

In the problem of Online Call Admission in Optical Networks, briefly called Oca, we are given a graph G = (V,E) together with a set of wavelengths W and a finite sequence σ = r1, r2, . . . of calls which arrive in an online fashion. Each call rj specifies a pair of nodes to be connected and an integral demand indicating the number of required lightpaths. A lightpath is a path in G together with...

We have developed an optimized cutting plane algorithm (OCA) for solving large-scale risk minimization problems. We prove that the number of iterations OCA requires to converge to a ε precise solution is approximately linear in the sample size. We also derive OCAS, an OCA-based linear binary Support Vector Machine (SVM) solver, and OCAM, a linear multi-class SVM solver. In an extensive empirica...

We investigate S-boxes defined by pairs of Orthogonal Cellular Automata (OCA), motivated the fact that such CA always define bijective vectorial Boolean functions, and could thus be interesting for design block ciphers. In particular, we perform an exhaustive search all nonlinear OCA diameter $$d=4$$ $$d=5$$ , which generate size $$6\times 6$$ $$8\times 8$$ respectively. Surprisingly, these tur...