recent developments in nanostructured products draw considerable attention to ultrafine grained materials. these materials are normally manufactured by different severe plastic deformation (spd) methods. in the present study, analytical models and finite element method (fem) are used to calculate strain imposed to a specimen that was deformed by equal channel angular pressing (ecap). in additio...

conclusions this study indicated that the rv systolic strain and strain rate can be used to detect early rv systolic dysfunction in ssc patients without pulmonary hypertension. these parameters may be useful for the provision of a more adequate management of ssc patients. results in the ssc patients, the rv strain (- 19 ± 10 vs. - 25 ± 4 %; p = 0.004) and the systolic strain rate (- 1.3 ± 0.5 v...

introduction: the term glaucoma refers to a group of diseases that have a characteristic optic neuropathy with associated visual field loss in common. intraocular pressure has been considered to be the only causal factor for glaucoma and the only factor that can be manipulated to alter the course of the disease. but considering high intraocular pressure as the only factor responsible for glauco...

Turner, J. R., J. M. Angle, E. D. Black, J. L. Joyal, D. B. Sacks, and J. L. Madara. PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase. Am. J. Physiol. 277 (Cell Physiol. 46): C554–C562, 1999.— The mechanisms by which protein kinase C (PKC) activation results in increased transepithelial resistance (TER) are unknown [G. Hecht, B. Robinson, and A. Koutsouris. Am...

Lu W, Ran P, Zhang D, Lai N, Zhong N, Wang J. Bone morphogenetic protein 4 enhances canonical transient receptor potential expression, store-operated Ca entry, and basal [Ca ]i in rat distal pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol 299: C1370–C1378, 2010. First published September 15, 2010; doi:10.1152/ajpcell.00040.2010.—Recent advances have identified an important rol...

The mechanisms by which protein kinase C (PKC) activation results in increased transepithelial resistance (TER) are unknown [G. Hecht, B. Robinson, and A. Koutsouris. Am. J. Physiol. 266 ( Gastrointest. Liver Physiol. 29): G214-G221, 1994]. We have previously shown that phosphorylation of the regulatory light chain of myosin II (MLC) is associated with decreases in TER and have suggested that c...

aims: the performance of the vision system as the most important sense of the body depends largely on the optimum lighting of an environment. it is one of the factors that lead to vision problems such as visual fatigue of employees. this study aimed to assess the local lighting and visual fatigue among the official staff of an automotive industry development and research center which was conduc...

background: this study was performed to induce conversion of rh strain tachyzoites of toxoplasma gondii to bradyzoites by ph changing of the cul­ture medium. methods: hela cell monolayers were infected at a 1:1 tachyzoite to cell ratio. four hours after infection, the culture medium was removed and re­placed with culture medium and 5% fcs, adjusted to ph 8 with naoh. the culture was maintained ...

Diarrhoeal disease is a major cause of illness and death among infants and young children worldwide. Among the Escherichia coli (E. coli) causing intestinal diseases, there are six well-described categories: enteroaggregative E. coli (EAEC), diffusely adherent E. coli (DAEC), enteroinvasive E. coli (EIEC), enteropathogenic E. coli (EPEC), enterohaemorrhagic E. coli (EHEC) and enterotoxigenic E....