UDP-galactopyranose mutase (UGM) plays an essential role in galactofuranose biosynthesis in pathogens by catalyzing the conversion of UDP-galactopyranose to UDP-galactofuranose. Here we report the first crystal structure of a covalent intermediate in the UGM reaction. The 2.3 Å resolution structure reveals UDP bound in the active site and galactopyranose linked to the FAD through a covalent bon...

A simplified method for the analysis of both the glyceride-rich Sf 20-1 O5 and the cholesterol-rich St 0-20 lowdensity lipoproteins is presented. It consists of serum lipoprotein fractionation by preparative ultracentrifugation and subsequent quantitative analysis by refractometry. Comparison of this technique with the technically more difficult analytic ultracentrifugal methodology reveals com...

The Size of the Shadow Economies of 145 Countries all over the World: First Results over the Period 1999 to 2003 Using the DYMIMIC approach, estimates of the shadow economy in 145 developing, transition, developed OECD countries, South Pacific islands and still communist countries are presented. The average size of the shadow economy (in percent of official GDP) over 2002/2003 in developing cou...

A new compound was confirmed to be formed at around the composition Li:Ti:Nb=19:10:12 in the system Li 0-Ti0 -Nb O5 by reaction at 1100 OC for 2 120 hrs in air betaeen tf2~63, Ti0 and Nb205. This compound was also produced by reactlon of L~N~o,.o.~T~o, with Li2Ti0 . Single crystals of the compound were grown uslng a Li2Mo04 8y flux method. The crystals were shown to possess a hexagonal symmetry...

The time-of-flight neutron Laue technique has been used to determine the location of hydrogen atoms in the enzyme d-xylose isomerase (XI). The neutron structure of crystalline XI with bound product, d-xylulose, shows, unexpectedly, that O5 of d-xylulose is not protonated but is hydrogen-bonded to doubly protonated His54. Also, Lys289, which is neutral in native XI, is protonated (positively cha...

In the title compound, C(23)H(23)NO(6)S, the plane of the N-phthalimido group makes a dihedral angle of 67.4 (1)° with the least square plane of the sugar ring defined by the C2, C3, C5 and O5 atoms using standard glucose nomenclature. The thio-ethyl group has the exo-anomeric conformation. In the crystal, inter-molecular hydrogen bonds involving the hy-droxy groups and the carbonyl O atoms of ...