The E1B-55-kDa protein of adenovirus type 5 and the p53 tumor suppressor gene product form a complex that localizes to the cytoplasm, thereby downregulating p53's transcriptional activity. The E4orf6 protein binds and relocalizes E1B-55-kDa, and the proteins act synergistically to inactivate p53. We show that another adenovirus E4 gene product, E4orf3, is also sufficient to relocalize E1B-55-kD...

Abstract Mechanism of the ion track formation in crystalline silicon (c-Si) is discussed, particularly under 1–9 MeV C 60 irradiation. In this energy region, was not expected because E much lower than threshold th = 17 determined by extrapolation from higher data past literature. The different between irradiations ions and monoatomic ions: tracks were observed 3 irradiation but 200 Xe ions, whi...

It is already well understood that unbinding materials and energy from their lithic reservoirs impacts upon Earth systems. But just the first stage of a cycle ‘Anthropocene trouble’. This paper tracks multiple ways in which subsequent system change reacts back social infrastructures subsurface exploitation landscapes they produce. Shifting fire regimes, intensifying hydrometeorological events s...

Nuclear emulsion, a tracking detector with sub-micron position resolution, has played a successful role in the field of particle physics and the analysis speed has been substantially improved by the development of automated scanning systems. This paper describes a newly developed automated scanning system and its application to the analysis of nuclear fragments emitted almost isotropically in n...

The sailing tracks of single otter trawl vessels were simulated using cubic hermite spline (cHs) interpolation method based on the automatic identification system (AIS) data of 6 sampled vessels that were fishing in the Zhoushan fishing grounds after the close of the fishing season from September 2012 to January 2013.  The vessels’ status (i.e. whether the vessels were fishing or not...

Background: Radon, an invisible, odorless, heaviest (nine times heavier than air) and radioactive gas is an aberration (the only gas in the long decay chain of heavy metal elements). It is ubiquitously present in dwellings and in the environment. Humans receive the greatest radiation dose in their homes. That's where they spend most time - typically 70%, more for small children. Recent worldwid...